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Key Documents

AB5414P

Sigma-Aldrich

Anti-Taurine Transporter Antibody

Chemicon®, from rabbit

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

rat, mouse

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
western blot: suitable

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... SLC6A6(6533)

Specificity

Recognizes Taurine Transporter. The immunogen shows no significant sequence homology with other known proteins.

SPECIES REACTIVITIES: The immunogen shows 100% sequence homology with mouse and 90% with human and canine. Reactivity with other species has not been confirmed.

Immunogen

A 20 amino acid peptide near the carboxy terminal cytoplasmic region of rat Taurine Transporter (Smith et al. 1992; Liu et al. 1993; Uchida et al. 1992; Jhiang et al. 1993).

Application

Anti-Taurine Transporter Antibody is an antibody against Taurine Transporter for use in ELISA & WB.
Western blot: 1-10 μg/mL using ECL. Tau1 is approx 65-70 kDa.

ELISA: 1:10,000-1:100,000 using 50-100 ng control peptide (Catalog Number AG341) per well.

Optimal working dilutions must be determined by the end user.

Storage and Stability

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For antibodies with volumes of 200 μL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container′s cap.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Renato Chaves Souto Branco et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 31(9), 4078-4087 (2017-06-03)
Taurine (Tau) restores β-cell function in obesity; however, its action is lost in malnourished obese rodents. Here, we investigated the mechanisms involved in the lack of effects of Tau in this model. C57BL/6 mice were fed a control diet (CD)
Ulrike Seidel et al.
Antioxidants (Basel, Switzerland), 9(11) (2020-11-05)
Taurine is a nonproteinogenic amino sulfonic acid in mammals. Interestingly, skeletal muscle is unable to synthesize taurine endogenously, and the processing of muscular taurine changes throughout ageing and under specific pathophysiological conditions, such as muscular dystrophy. Ageing and disease are
Eliza R McColl et al.
American journal of reproductive immunology (New York, N.Y. : 1989), 81(6), e13115-e13115 (2019-03-30)
Maternal immune activation (MIA) during pregnancy is associated with increased chances of neurodevelopmental disorders including schizophrenia and autism spectrum disorder (ASD). However, the exact mechanism through which MIA contributes to altered neurodevelopment is unknown. Due to the important role that
Kiren Ubhi et al.
The European journal of neuroscience, 39(6), 1026-1041 (2013-12-07)
MicroRNA (miRNA) are short sequences of RNA that function as post-transcriptional regulators by binding to target mRNA transcripts resulting in translational repression. A number of recent studies have identified miRNA as being involved in neurodegenerative disorders including Alzheimer's disease, Parkinson's

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