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Key Documents

AB5398P

Sigma-Aldrich

Anti-Vanilloid Receptor Like Protein Antibody, pain, CT

Chemicon®, from rabbit

Synonym(s):

VRL-1

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

rat

should not react with

human

manufacturer/tradename

Chemicon®

technique(s)

immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

NCBI accession no.

NM_016113.3

UniProt accession no.

Q9Y5S1

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... TRPV2(51393)

Specificity

Vanilloid receptor like protein 1 (VRL-1). Immunohistochemical analysis of rat dorsal root ganglia and spinal cord indicates specific staining in a subpopulation of sensory neurons.

Immunogen

Epitope: C-terminus
Peptide corresponding to the C-terminal 18 amino acids of the rat VRL-1 protein sequence (Acc#: AAD26364). This immunogen sequence is 100% conserved in the mouse growth factor regulated calcium channel (Acc#: AB021665)

Application

Anti-Vanilloid Receptor Like Protein Antibody, pain, C-terminus is an antibody against Vanilloid Receptor Like Protein for use in WB, IC, IH.
Research Category
Neuroscience
Research Sub Category
Neuroinflammation & Pain

Neurotransmitters & Receptors
Western blot: 0.5-1 μg/mL

Immunohistochemistry: 0.5-1.0 μg/mL on rat dorsal root ganglia and spinal cord.

Immunocytochemistry: 0.5-1.0 μg/mL on rat dorsal root ganglia and spinal cord.

Optimal working dilutions must be determined by end user.

Physical form

Affinity purified immunoglobulin. Lyophilized. Contains no preservative. Reconstitute with 20 μL of sterile distilled water. Centrifuge if necessary to remove any residue.

Storage and Stability

Maintain lyophilized material at -20°C to -70°C for up to 6 months after date of receipt. After reconstitution maintain frozen at -20°C in undiluted aliquots for up to 6 months. Glycerol (1:1) can be assed to additional stability. Avoid repeated freeze/thaw cycles.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Karl-Erik Andersson et al.
BJU international, 106(8), 1114-1127 (2010-12-16)
• The pathophysiology of lower urinary tract symptoms (LUTS), detrusor overactivity (DO), and the overactive bladder (OAB) syndrome is multifactorial and remains poorly understood. • The transient receptor potential (TRP) channel superfamily has been shown to be involved in nociception

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