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Sigma-Aldrich

Fmoc-Phe(4-Cl)-OH

Novabiochem®

Synonym(s):

Fmoc-Phe(4-Cl)-OH, N-α-Fmoc-4-chloro-L-phenylalanine

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About This Item

Empirical Formula (Hill Notation):
C24H20ClNO4
CAS Number:
Molecular Weight:
421.87
MDL number:
UNSPSC Code:
12352209
NACRES:
NA.22

Quality Level

product line

Novabiochem®

Assay

≥95.0% (acidimetric)
≥98% (TLC)
≥98.0% (HPLC)

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

mp

138 °C

application(s)

peptide synthesis

functional group

chloro

storage temp.

2-30°C

InChI

1S/C24H20ClNO4/c25-16-11-9-15(10-12-16)13-22(23(27)28)26-24(29)30-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-12,21-22H,13-14H2,(H,26,29)(H,27,28)/t22-/m0/s1

InChI key

CQPNKLNINBUUOM-QFIPXVFZSA-N

General description

Standard building block for introduction of 4-chlorophenylalanine residues by Fmoc SPPS.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Linkage

Replaces: 04-12-1096

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(157B)): ≥ 98 %
Purity (TLC(CMA2)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 95.0 %
Water (K. F.): ≤ 3.0 %

To see the solvent systems used for TLC of Novabiochem® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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