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6.18607

Sigma-Aldrich

Methanol

for chromatography, LiChrosolv®

Synonym(s):

Methanol, Methyl alcohol

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About This Item

Linear Formula:
CH3OH
CAS Number:
67-56-1
Molecular Weight:
32.04
Beilstein:
1098229
MDL number:
MFCD00004595
UNSPSC Code:
12191601

grade

for chromatography

Quality Level

100

vapor density

1.11 (vs air)

vapor pressure

410 mmHg ( 50 °C)
97.68 mmHg ( 20 °C)

product line

LiChrosolv®

autoignition temp.

725 °F

expl. lim.

36 %

refractive index

n20/D 1.329 (lit.)

bp

64.7 °C (lit.)

mp

−98 °C (lit.)

density

0.791 g/mL at 25 °C (lit.)

SMILES string

CO

InChI

1S/CH4O/c1-2/h2H,1H3

InChI key

OKKJLVBELUTLKV-UHFFFAOYSA-N

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General description

Methanolis a high-purity solvent specifically designed for chromatographicapplications. It is used as a mobile phase component in high-performance liquidchromatography (HPLC), gas chromatography (GC), and thin-layer chromatography(TLC).

Application

Methanolcan be used as a derivatization solvent to form the methylated derivatives oftopiramate that can be analyzed using gas chromatography-mass spectrometry(GC-MS) for qualitative and quantitative determination of topiramate in serumsamples.

Legal Information

LICHROSOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes,Central nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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A capillary GC method using nitrogen phosphorus detection for determination of topiramate in patients with epilepsy
Malakova J, et al.
Chromatographia, 66, 363-367 (2007)
Multi-walled carbon nanotubes packed cartridge for the solid-phase extraction of several phthalate esters from water samples and their determination by high performance liquid chromatography
Cai Ya-Qi, et al.},
Analytica Chimica Acta, 494(1-2), 149-156 (2003)

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