07-2264

Anti-OSR1 Antibody

from rabbit, purified by affinity chromatography

• Synonym(s): oxidative-stress responsive 1, serine/threonine-protein kinase OSR1, Oxidative stress-responsive 1 protein
• UNSPSC Code: 12352203
• eCl@ss: 32160702

Properties

• biological source: rabbit
• Quality Level: 100
• antibody product type: primary antibodies
• clone: polyclonal
• purified by: affinity chromatography
• species reactivity: mouse, human
• technique(s): western blot: suitable
• NCBI accession no.: NP_005100
• UniProt accession no.: O95747
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... OSR1(130497) , OXSR1(9943)

Description

General description

Odd-skipped-related protein 1 (OSR1) is expressed during the beginning stages of embryogenesis in the intermediate mesoderm and in patterns during limb and branchial arch development. It has been shown that OSR1 plays a critical part in creating kidney precursor cells and regulating differentiation into kidney tubular tissue. OSR1 may play a role in limiting endoderm differentiation from mesendoderm. Expression of OSR1 is controlled by Runx2 and Ikzf1 and is key in development of embryonic, heart and urogenital tissue.

Specificity

Other homologies: Rat (96% sequence homology).

Immunogen

GST-tagged recombinant protein corresponding to human OSR1.

Application

Detect the OSR1 protein using this Anti-OSR1 validated for use in WB.

Research Category
Signaling

Research Sub Category
Developmental Signaling

Quality

Evaluated by Western Blot in HEK293 cell lysate.

Western Blot Analysis: 1:1,000 dilution of this antibody detected OSR1 on 10 µg of HEK293 cell lysate.

Target description

~58 kDa observed

Physical form

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
HEK293 cell lysate

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable