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E-081

Supelco

Etizolam solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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$222.00

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1 ML
$222.00

About This Item

Empirical Formula (Hill Notation):
C17H15ClN4S
CAS Number:
40054-69-1
Molecular Weight:
342.85
MDL number:
MFCD00867532
UNSPSC Code:
41116107
PubChem Substance ID:
329798867
NACRES:
NA.24

$222.00

Available to ship onApril 23, 2025Details

Request a Bulk Order

grade

certified reference material

Quality Level

300

form

liquid

feature

(Snap-N-Spike®)

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule B (Switzerland)

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

SMILES string

CCC1=CC2=C(S1)N3C(CN=C2C4=CC=CC=C4Cl)=NN=C3C

InChI

1S/C17H15ClN4S/c1-3-11-8-13-16(12-6-4-5-7-14(12)18)19-9-15-21-20-10(2)22(15)17(13)23-11/h4-8H,3,9H2,1-2H3

InChI key

VMZUTJCNQWMAGF-UHFFFAOYSA-N

Related Categories

General description

A certified solution standard for use in LC/MS or GC/MS benzodiazepine testing methods in clinical toxicology, urine drug testing, or forensic analysis. Etizolam, sold under brand names such as Etilaam, Etizola, or Depas, is a benzodiazepine analog used for the short-term treatment of insomnia, anxiety, or panic attacks. Etizolam is also sold on the designer drug market with cases of abuse noted in Europe and the US.

Biochem/physiol Actions

Etizolam is a thienodiazepine anxiolytic and as compared to other benzodiazepines has lower dependence potential. It differs from other benzodiazepines in that its molecules possess a thiophene ring instead of benzene. It has anticonvulsant, sedative, anxiolytic, amnesic, hypnotic and muscle relaxant properties. It′s mode of action is through benzodiazepine receptor. It is used to treat insomnia, moderate depression and social anxiety disorder, and has occasionally been associated with blepharospasm and skin lesions.[1][2]

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

49.5 °F

Flash Point(C)

9.7 °C

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Takeshi Terao et al.
Progress in neuro-psychopharmacology & biological psychiatry, 31(1), 295-296 (2006-08-19)
A 65-year-old female patient with major depressive disorder suffered from clonus, shivering and impaired visual acuity after 20 mg/day of paroxetine administration. The symptoms were initially regarded as further manifestations of her somatic symptoms of depression, and paroxetine was increased
Akira Watanabe et al.
Nihon Arukoru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studies & drug dependence, 39(5), 482-487 (2004-12-03)
Drug dependence is a social problem of over the world and resistant to medical intervention by psychiatrist as well as general clinicians. In Japan, methamphetamine dependence is one of the most critical social problems, but opioid dependence is relatively rare.
Naoko Tanaka et al.
Soudni lekarstvi, 56(3), 38-39 (2011-09-06)
A fatal poisoning case involving etizolam, phenobarbital, promethazine and chlorpromazine is presented. Quantitative toxicological analysis showed that the concentrations of etizolam, phenobarbital, promethazine and chlorpromazine in the femoral blood were 86 ng/ml, 5082 microg/ml, 0.107 microg/ml and 0.144 microg/ml, respectively
Minoru Narita et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 31(4), 739-750 (2005-08-27)
Clinically, it has been reported that chronic pain induces depression, anxiety, and reduced quality of life. The endogenous opioid system has been implicated in nociception, anxiety, and stress. The present study was undertaken to investigate whether chronic pain could induce
Akira Namera et al.
Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology, 24(1), 27-34 (2011-04-13)
The immunoassay screening of benzodiazepines in urine is one of the most important methods of drug analysis in clinical and forensic laboratories. We experienced an unusual case of poisoning wherein the result of Triage DOA immunoassay screening was negative, although
View All Related Papers

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