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860693P

Avanti

C24:0 Ceramide (d18:2(4E,8Z)/24:0)

Avanti Research - A Croda Brand 860693P, powder

Synonym(s):

N-lignoceroyl-D-erythro-sphingosine (d18:2(4E,8Z) base)

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About This Item

Empirical Formula (Hill Notation):
C42H81NO3
Molecular Weight:
648.10
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 1 mg (860693P-1mg)

manufacturer/tradename

Avanti Research - A Croda Brand 860693P

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

OC[C@@](NC(CCCCCCCCCCCCCCCCCCCCCCC)=O)([H])[C@]([H])(O)/C=C/CC/C=C\CCCCCCCCC

General description

C24:0 Ceramide (d18:2(4E,8Z)/24:0), also known as N-lignoceroyl-D-erythro-sphingosine (d18:2(4E,8Z) base), is a very long chain plasma ceramide derived from sphingosine containing two double bonds with lignoceric acid.

Biochem/physiol Actions

Altered levels of C24:0 Ceramide has been observed in mild cognitive impairment (MCI) patients. It acts as a primary biomarker of Alzheimer disease (AD) progression.

Packaging

5 mL Amber Glass Screw Cap Vial (860693P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

No data available

Flash Point(C)

No data available


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Michelle M Mielke et al.
Alzheimer's & dementia : the journal of the Alzheimer's Association, 6(5), 378-385 (2010-09-04)
A blood-based biomarker of Alzheimer's disease (AD) would be superior to cerebrospinal fluid (CSF) and neuroimaging measures in terms of cost, invasiveness, and feasibility for repeated measures. We previously reported that blood ceramides varied in relation to timing of memory

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