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860583P

Avanti

12:0 SM (d18:1/12:0)

Avanti Research™ - A Croda Brand 860583P, powder

Synonym(s):

N-lauroyl-D-erythro-sphingosylphosphorylcholine

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About This Item

Empirical Formula (Hill Notation):
C35H71N2O6P
CAS Number:
474923-21-2
Molecular Weight:
646.92
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 10 mg (860583P-10mg)
pkg of 1 × 25 mg (860583P-25mg)
pkg of 1 × 5 mg (860583P-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 860583P

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCC)=O)COP([O-])(OCC[N+](C)(C)C)=O

InChI

1S/C35H71N2O6P/c1-6-8-10-12-14-16-17-18-19-21-22-24-26-28-34(38)33(32-43-44(40,41)42-31-30-37(3,4)5)36-35(39)29-27-25-23-20-15-13-11-9-7-2/h26,28,33-34,38H,6-25,27,29-32H2,1-5H3,(H-,36,39,40,41)/b28-26+/t33-,34+/m0/s1

InChI key

HZCLJRFPXMKWHR-FEBLJDHQSA-N

Application

12:0 SM (d18:1/12:0) has been used:
  • as a lipid standard in the optimization of the liquid chromatography-mass spectrometry (LC-MS) method conditions
  • as an internal standard for the quantification of serum cholesterol and triacylglycerol using liquid chromatography-mass spectrometry (LC-MS) preceded by single-step liquid-liquid extraction method
  • as an internal standard for tandem mass spectrometry analysis of lipid species

Packaging

5 mL Amber Glass Screw Cap Vial (860583P-10mg)
5 mL Amber Glass Screw Cap Vial (860583P-25mg)
5 mL Amber Glass Screw Cap Vial (860583P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Ursula Loizides-Mangold et al.
Journal of lipid research, 53(8), 1522-1534 (2012-05-26)
Glycosylphosphatidylinositol (GPI) anchor biosynthesis takes place in the endoplasmic reticulum (ER). After protein attachment, the GPI anchor is transported to the Golgi where it undergoes fatty acid remodeling. The ER exit of GPI-anchored proteins is controlled by glycan remodeling and
Liang Gao et al.
Metabolomics : Official journal of the Metabolomic Society, 16(5), 53-53 (2020-04-19)
High quality data, based on reliable quantification and clear identification of the reported lipid species, are required for the clinical translation of human plasma lipidomic studies. Lipid quantification can be efficiently performed on triple quadrupole (QqQ) mass spectrometers in targeted
Elisabetta Albi et al.
International journal of molecular sciences, 15(7), 11555-11565 (2014-07-01)
Proliferating thyroid cells are more sensitive to UV-C radiations than quiescent cells. The effect is mediated by nuclear phosphatidylcholine and sphingomyelin metabolism. It was demonstrated that proton beams arrest cell growth and stimulate apoptosis but until now there have been
Felicitas S Boretti et al.
Metabolomics : Official journal of the Metabolomic Society, 16(1), 1-1 (2019-12-05)
Food and dietary ingredients have significant effects on metabolism and health. To evaluate whether and how different diets affected the serum lipidomic profile of dogs. Sixteen healthy beagles were fed a commercial dry diet for 3 months (control diet). After an
Jinfeng Huang et al.
Dose-response : a publication of International Hormesis Society, 18(2), 1559325820914209-1559325820914209 (2020-05-05)
Radiation biodosimeters are required urgently for fast and accurate evaluation of absorbed dose for irradiated individuals. Lipidomics has appeared as a credible technique for identification and quantification of lipid for researching biomarker of diseases. We performed a lipidomic profile on
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