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860573P

Avanti

C12 Mono-Sulfo Galactosyl(β) Ceramide (d18:1/12:0)

Avanti Research™ - A Croda Brand 860573P, powder

Synonym(s):

3-O-sulfo-D-galactosyl-β1-1′-N-lauroyl-D-erythro-sphingosine (ammonium salt), (synthetic)

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About This Item

Empirical Formula (Hill Notation):
C36H72N2O11S
CAS Number:
852043-39-1
Molecular Weight:
741.03
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 1 mg (860573P-1mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 860573P

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](OS([O-])(=O)=O)[C@H]([C@H]1CO)O.[NH4+]

InChI

1S/C36H69NO11S.H3N/c1-3-5-7-9-11-13-14-15-16-18-19-21-23-25-30(39)29(37-32(40)26-24-22-20-17-12-10-8-6-4-2)28-46-36-34(42)35(48-49(43,44)45)33(41)31(27-38)47-36;/h23,25,29-31,33-36,38-39,41-42H,3-22,24,26-28H2,1-2H3,(H,37,40)(H,43,44,45);1H3/b25-23+;/t29-,30+,31?,33-,34?,35?,36+;/m0./s1

InChI key

ZRHCDEVQWSMWDC-LNTPIPJUSA-N

Application

C12 Mono-Sulfo Galactosyl(β) Ceramide (d18:1/12:0) is suitable for use as a standard in mass spectrometric analysis of sulfatides.

Biochem/physiol Actions

C12 Mono-Sulfo Galactosyl(β) Ceramide (d18:1/12:0) is a non-physical sulfatide. Accumulation of sulfatide impairs the activity of arylsulfatase A enzyme, which in turn leads to the development of genetic disease, metachromatic leukodystrophy.

Packaging

5 mL Amber Glass Screw Cap Vial (860573P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Quantification of plasma sulfatides by mass spectrometry: Utility for metachromatic leukodystrophy
Saville J, et al.
Analytica Chimica Acta, 955, 79-85 (2017)
Synthetic sulfogalactosylceramide (sulfatide) and its use for the mass spectrometric quantitative urinary determination in metachromatic leukodystrophies
Cui Y, et al.
Glycoconjugate Journal, 25(2), 147-155 (2008)
Mariachiara Bianco et al.
Food chemistry, 324, 126878-126878 (2020-04-29)
Ceramides (Cer) and cerebrosides are important sphingolipids (SL) involved in many biological processes. Herein, the SL content of yellow lupin seeds (Lupinus luteus) was determined by liquid-liquid extraction, mild alkaline hydrolysis (1 h at 37 °C) and reversed-phase liquid chromatography with negative
Michela Antonelli et al.
Analytical and bioanalytical chemistry, 412(2), 413-423 (2019-11-25)
The chemical composition of Cannabis sativa L. has been extensively investigated for several years; nevertheless, a detailed lipidome characterization is completely lacking in the literature. To achieve this goal, an extraction and enrichment procedure was developed for the characterization of

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