850092P

Brain Lyso PS

Avanti Research^™ - A Croda Brand 850092P, powder

• Synonym(s): L-α-lysophosphatidylserine (Brain, Porcine) (sodium salt)
• CAS Number: 383907-66-2
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• Assay: >99% (LPS; may contain up to 10% of the 2-LPS isomer, TLC)
• form: powder
• packaging: pkg of 1 × 10 mg (850092P-10mg); pkg of 1 × 5 mg (850092P-5mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 850092P
• lipid type: phosphoglycerides
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: O[C@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)([H])COC(CCCCCCCCCCCCCCCCC)=O.[Na+]
• InChI: 1S/C24H48NO9P.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-23(27)32-18-21(26)19-33-35(30,31)34-20-22(25)24(28)29;/h21-22,26H,2-20,25H2,1H3,(H,28,29)(H,30,31);/q;+1/p-1/t21-,22+;/m1./s1
• InChI key: SVSJEWKLQKWQOV-NSLUPJTDSA-M

Description

General description

Lyso-phosphatidylserine (lyso-PS) is produced by the enzymatic action of phospholipase A1 and A2 on phosphatidylserine.[1]

Application

Brain Lyso PS is suitable for use:

• as standard to quantify lipids using ultra high performance liquid chromatography-electrospray ionization-tandem mass spectrometry (UHPLC-ESI-MS/MS)[2]
• in the preparation of liposomes for coating dynabeads for binding of factor H (fH)[3]
• as a ligand for G-protein coupled receptor 34 (GPR34) in in vitro experiments to investigate its effect granulosa cells(GC) and hormone production[4]
• as substrate for sicariid phospholipase D (PLD) toxins (SicTox) enzymes[5]

Biochem/physiol Actions

Lyso-Phosphatidylserine (Lyso-PS) plays a key role in histamine release from mast cells. Lyso-PS inhibits the growth to T cells. It is a chemotactic substance for fibroblast and tumor cells.[1] Lyso-PS is involved in tumor progression and allergic reactions.[6]

Packaging

5 mL Amber Glass Screw Cap Vial (850092P-10mg)

5 mL Amber Glass Screw Cap Vial (850092P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids