791639C
Avanti
15:0-18:1-d7-PS
Avanti Research™ - A Croda Brand
Synonym(s):
1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-phospho-L-serine (sodium salt)
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About This Item
Empirical Formula (Hill Notation):
C39H66 D7 NNaO10 P
CAS Number:
Molecular Weight:
777.00
UNSPSC Code:
12352211
NACRES:
NA.25
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Assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 1 mL (791639C-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
concentration
1 mg/mL (791639C-1mg)
shipped in
dry ice
storage temp.
−20°C
General description
1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-phospho-L-serine (sodium salt) is a is a deuterated phospholipid. The lipid comprises phosphatidylserine attached to pentadecanoic acid and oleic acid. Oleic acid harbors the deuterium ions. Phosphatidylserine is a component of inner cell membrane and is present in metabolically active sites. It is enriched in myelin sheath and is an acidic phospholipid.
This deuterium labeled lipid is also available in a formulation of multiple lipid standards. The SPLASH™ LIPIDOMIX™ Standard includes all of the major lipid classes at ratios relative to human plasma, allowing one easy internal standard solution to be added to every sample.
Application
15:0-18:1-d7-PS (1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-phospho-L-serine (sodium salt)) has been used:
- as a component of extraction solvent for lipid isolation from biological samples
- as an internal standard to spike cell lysate and to quantify lipid species using fourier transform mass spectrometry (FTMS) analysis
- as an internal standard to spike liver homogenate to quantify lipids by shotgun-electrospray ionization tandem mass spectrometry (ESI-MS)
Biochem/physiol Actions
Phosphatidylserine (PS) coordinates many regulatory functions and is a modulator of enzymes, channels and various receptors. PS supplementation provides relief from exercise induced stress. PS is essential for neurotransmission, prevents nerve cell deterioration and supports cognitive functionality.
Packaging
2 mL Amber Glass Sealed Ampule (791639C-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
LIPIDOMIX is a trademark of Avanti Polar Lipids, LLC
SPLASH is a trademark of Avanti Polar Lipids, LLC
also commonly purchased with this product
Product No.
Description
Pricing
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
Target Organs
Central nervous system
Storage Class Code
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK
WGK 3
Flash Point(F)
does not flash
Flash Point(C)
does not flash
Certificates of Analysis (COA)
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Michael A Starks et al.
Journal of the International Society of Sports Nutrition, 5, 11-11 (2008-07-30)
Previous research has indicated that phosphatidylserine (PS) supplementation has the potential to attenuate the serum cortisol response to acute exercise stress. Equivocal findings suggest that this effect might be dose dependent. This study aimed to examine the influence of short-term
Impact of plant polyphenols on triacylglycerols and phos-pholipids in rat liver fed with high fat diet
Ma HF, et al.
OIL CROP SCIENCE, 4, 251-264 (2017)
Tong Liu et al.
Expert review of proteomics, 17(3), 233-242 (2020-04-21)
Background: Colorectal cancer (CRC) represents a third leading cause of cancer-related death worldwide. The reliable diagnostic biomarkers for detecting CRC at early stage is critical for decreasing the mortality.Method: A conjunctive lipidomic approach was employed to investigate the differences in
Michael J Glade et al.
Nutrition (Burbank, Los Angeles County, Calif.), 31(6), 781-786 (2015-05-03)
The aim of this study was to assess the roles and importance of phosphatidylserine (PS), an endogenous phospholipid and dietary nutrient, in human brain biochemistry, physiology, and function. A scientific literature search was conducted on MEDLINE for relevant articles regarding
Chuchu Wang et al.
Nature communications, 11(1), 1531-1531 (2020-03-27)
Vesicle associated membrane protein 2 (VAMP2/synaptobrevin2), a core SNARE protein residing on synaptic vesicles (SVs), forms helix bundles with syntaxin-1 and SNAP25 for the SNARE assembly. Prior to the SNARE assembly, the structure of VAMP2 is unclear. Here, by using
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