H52406
3-(4-Hydroxyphenyl)propionic acid
98%
Synonym(s):
3-(p-Hydroxyphenyl)propionic acid, Phloretic acid
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All Photos(3)
About This Item
Linear Formula:
HOC6H4CH2CH2CO2H
CAS Number:
Molecular Weight:
166.17
Beilstein:
2209841
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Assay
98%
mp
129-131 °C (lit.)
fluorescence
λex 320 nm; λem 404 nm (buffer, pH 8.6)
SMILES string
OC(=O)CCc1ccc(O)cc1
InChI
1S/C9H10O3/c10-8-4-1-7(2-5-8)3-6-9(11)12/h1-2,4-5,10H,3,6H2,(H,11,12)
InChI key
NMHMNPHRMNGLLB-UHFFFAOYSA-N
Application
3-(4-Hydroxyphenyl)propionic acid can be used:
- To derive hydrogel based on chitosan, gelatin or poly(ethylene glycol).
- To synthesize novel symmetric and asymmetric bolaamphiphiles.
- As an acyl donor for the enzymatic synthesis of sugar alcohol esters.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Biocatalytic acylation of sugar alcohols by 3-(4-hydroxyphenyl) propionic acid.
Croitoru R, et al.
Process Biochemistry (Oxford, United Kingdom), 47(12), 1894-1902 (2012)
Efficient syntheses of bolaform surfactants from L-rhamnose and/or 3-(4-hydroxyphenyl) propionic acid.
Akong F O and Bouquillon S
Green Chemistry, 17(6), 3290-3300 (2015)
Seon-Min Jeon et al.
Translational research : the journal of laboratory and clinical medicine, 149(1), 15-21 (2007-01-02)
This study was conducted to compare the hypocholesterolemic and antioxidant effects of naringenin (0.02%), and its metabolites, rho-hyproxyphenylpropionic acid (PHPP, 0.012%) and rho-hydroxybenzoic acid (PHB, 0.012%), in 1% cholesterol diet-fed rats. All supplements significantly lowered the plasma total-cholesterol (total-C), triglyceride
Eliana Capecchi et al.
Nanomaterials (Basel, Switzerland), 8(6) (2018-06-20)
Sustainable catalysts for the oxidation of phenol derivatives under environmentally friendly conditions were prepared by the functionalization of lignin nanoparticles with tyrosinase. Lignin, the most abundant polyphenol in nature, is the main byproduct in the pulp and paper manufacturing industry
Tailorable cell culture platforms from enzymatically cross-linked multifunctional poly (ethylene glycol)-based hydrogels.
Menzies D J, et al.
Biomacromolecules, 14(2), 413-423 (2013)
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