Skip to Content
MilliporeSigma
All Photos(1)

Documents

D219800

Sigma-Aldrich

1,3-Di-p-tolylcarbodiimide

96%

Synonym(s):

N,N′-Methanetetraylbis[4-methyl]benzenamine, Bis(4-methylphenyl)carbodiimide, NSC 20627

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
CH3C6H4N=C=NC6H4CH3
CAS Number:
726-42-1
Molecular Weight:
222.29
EC Number:
211-971-7
MDL number:
MFCD00010701
UNSPSC Code:
12352002
PubChem Substance ID:
24893653
NACRES:
NA.22

Assay

96%

form

powder

reaction suitability

reaction type: Coupling Reactions

bp

221-223 °C/20 mmHg (lit.)

mp

56-58 °C (lit.)

application(s)

peptide synthesis

storage temp.

2-8°C

SMILES string

Cc1ccc(cc1)N=C=Nc2ccc(C)cc2

InChI

1S/C15H14N2/c1-12-3-7-14(8-4-12)16-11-17-15-9-5-13(2)6-10-15/h3-10H,1-2H3

InChI key

BOSWPVRACYJBSJ-UHFFFAOYSA-N

Application

Reactant for synthesis of:
  • Cyclic guanidines
  • Five membered heterometallacycloallenes
  • Benzimidazoles or quinazolines via nucleophilic addition and intramolecular C-C bond formation
  • Benzoxazole and benzimidazole derivatives via cross-coupling reactions
  • Gem-difluorodihydrouracil derivatives via addition reactions

Reactant for ketene cycloadditions

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Thi Kim Hoang Trinh et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 25(39), 9242-9252 (2019-04-26)
In the search of smarter routes to control the conditions of N-heterocyclic carbene (NHCs) formation, a two-component air-stable NHC photogenerating system is reported. It relies on the irradiation at 365 nm of a mixture of 2-isopropylthioxanthone (ITX) with 1,3-bis(mesityl)imidazoli(ni)um tetraphenylborate. The

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service