777129
N,N-Diethylmethacrylamide
contains <500 ppm MEHQ as inhibitor, 97%
Synonym(s):
DEMAAM, DEMAM
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About This Item
Empirical Formula (Hill Notation):
C8H15NO
CAS Number:
Molecular Weight:
141.21
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23
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Assay
97%
form
liquid
contains
<500 ppm MEHQ as inhibitor
refractive index
n20/D 1.455
density
0.901 g/mL at 25 °C
storage temp.
2-8°C
SMILES string
CCN(CC)C(=O)C(C)=C
InChI
1S/C8H15NO/c1-5-9(6-2)8(10)7(3)4/h3,5-6H2,1-2,4H3
InChI key
JMCVCHBBHPFWBF-UHFFFAOYSA-N
General description
Post polymerization, N, N-Diethyl methacrylamide gels show temperature sensitivity because of their lower critical solution temperature (LCST). This acrylamide is commonly polymerized to form temperature sensitive hydrogels. The presence of a hydrophobic group (methyl and ethyl group in this case) is characteristic in temperature sensitive polymers. Water solubility in such polymers decreases with increase in temperature.
Application
Since the lower critical solution temperature (LCST) is around body temperature, it is widely used in the development of drug delivery systems based on the sol gel phase conversion at body temperature.
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
183.0 °F
Flash Point(C)
83.88 °C
Certificates of Analysis (COA)
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Environmentally sensitive hydrogels have enormous potential in various applications. Some environmental variables, such as low pH and elevated temperatures, are found in the body. For this reason, either pH-sensitive and/or temperature-sensitive hydrogels can be used for site-specific controlled drug delivery.
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