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About This Item
Linear Formula:
F2C6H3NCS
CAS Number:
Molecular Weight:
171.17
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
Recommended Products
Assay
98%
refractive index
n20/D 1.598 (lit.)
bp
46-48 °C/0.5 mmHg (lit.)
density
1.349 g/mL at 25 °C (lit.)
SMILES string
Fc1ccc(N=C=S)c(F)c1
InChI
1S/C7H3F2NS/c8-5-1-2-7(10-4-11)6(9)3-5/h1-3H
InChI key
ABGGPKIFVAIRGU-UHFFFAOYSA-N
General description
2,4-Difluorophenyl isothiocyanate is a fluorinated building block. Its enthalpy of vaporization at boiling point (490.15K) has been reported to be 42.939kjoule/mol.
Application
2,4-Difluorophenyl isothiocyanate may be used in the synthesis of the following 2-(4-(4-X-phenylsulfonyl)benzoyl)-N-(2,4-difluorophenyl)hydrazinecarbothioamides:
- N-(2,4-difluorophenyl)-2-(4-(phenylsulfonyl)benzoyl)hydrazinecarbothioamide
- 2-(4-(4-chlorophenylsulfonyl)benzoyl)-N-(2,4-difluorophenyl)hydrazinecarbothioamide
- 2-(4-(4-bromophenylsulfonyl)benzoyl)-N-(2,4-difluorophenyl)hydrazinecarbothioamide
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
199.4 °F - closed cup
Flash Point(C)
93 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Stefania-Felicia Barbuceanu et al.
International journal of molecular sciences, 15(6), 10908-10925 (2014-06-19)
In the present investigation, new hydrazinecarbothioamides 4-6 were synthesized by reaction of 4-(4-X-phenylsulfonyl)benzoic acids hydrazides (X=H, Cl, Br) 1-3 with 2,4-difluorophenyl isothiocyanate and further these were treated with sodium hydroxide to obtain 1,2,4-triazole-3-thione derivatives 7-9. The reaction of 7-9 with
Yaws CL.
Thermophysical Properties of Chemicals and Hydrocarbons, 535-535 (2014)
Fazila Rizvi et al.
Scientific reports, 9(1), 6738-6738 (2019-05-03)
A library of thiosemicarbazide derivatives of isoniazid 3-27, was synthesized and evaluated for their anti-inflammatory and urease inhibition activities, by using in vitro bioassays. Among these compounds 9, 10, 12, 21, and 26 were identified as new derivatives. Prolonged use
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