456233
L-Aspartic acid dimethyl ester hydrochloride
97%
Synonym(s):
Dimethyl L-aspartate hydrochloride, L-Asp(OMe)OMe·HCl
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About This Item
Linear Formula:
CH3O2CCH2CH(NH2)CO2CH3 · HCl
CAS Number:
Molecular Weight:
197.62
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.22
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Assay
97%
form
solid
reaction suitability
reaction type: solution phase peptide synthesis
mp
115-117 °C (lit.)
application(s)
peptide synthesis
SMILES string
Cl.COC(=O)C[C@H](N)C(=O)OC
InChI
1S/C6H11NO4.ClH/c1-10-5(8)3-4(7)6(9)11-2;/h4H,3,7H2,1-2H3;1H/t4-;/m0./s1
InChI key
PNLXWGDXZOYUKB-WCCKRBBISA-N
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Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Soojin Kim et al.
Pharmaceutics, 12(9) (2020-09-10)
An elevated level of endoplasmic reticulum (ER) stress is considered an aggravating factor for inflammatory bowel disease (IBD). To develop an ER-stress attenuator that is effective against colitis, 4-phenylbutyric acid (4-PBA), a chemical chaperone that alleviates ER stress, was conjugated
Wooseong Kim et al.
Molecular pharmaceutics, 16(9), 4007-4016 (2019-08-07)
We investigated if the therapeutic switching of sofalcone (SFC), a gastroprotective agent, to an anticolitic agent is feasible using colon-targeted drug delivery. SFC can activate the anti-inflammatory nuclear factor (erythroid-derived 2)-like 2 (Nrf2)-hemeoxygenase-1 (HO-1) pathway in human colon epithelial cells
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