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259640

Sigma-Aldrich

4-Nitrobenzoic hydrazide

98%

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About This Item

Linear Formula:
O2NC6H4CONHNH2
CAS Number:
Molecular Weight:
181.15
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:

Assay

98%

form

solid

mp

218 °C (dec.) (lit.)

solubility

acetone: soluble 0.5 g/10 mL, clear, yellow

SMILES string

NNC(=O)c1ccc(cc1)[N+]([O-])=O

InChI

1S/C7H7N3O3/c8-9-7(11)5-1-3-6(4-2-5)10(12)13/h1-4H,8H2,(H,9,11)

InChI key

FKZXYJYTUSGIQE-UHFFFAOYSA-N

Application

4-Nitrobenzoic hydrazide has been used as internal standard in determination of isoniazid in human plasma by LC-MS/MS method.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 877(3), 285-290 (2008-12-30)
An LC-MS/MS method for the determination of isoniazid in human plasma was developed and validated. Human plasma aliquots of 100 microL were used for analysis. The assay used nialamide as the internal standard. The calibration curve concentration range was 50-10,000

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