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218472

Sigma-Aldrich

Tetramethyl orthosilicate

98%

Synonym(s):

Tetramethoxysilane

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$132.00
500 G
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100 G
$132.00
500 G
$326.00

About This Item

Linear Formula:
Si(OCH3)4
CAS Number:
Molecular Weight:
152.22
Beilstein:
1699658
EC Number:
MDL number:
UNSPSC Code:
12352103
PubChem Substance ID:
NACRES:
NA.23

$132.00


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vapor density

5.25 (vs air)

Quality Level

vapor pressure

13 hPa ( 20 °C)

Assay

98%

form

liquid

refractive index

n20/D 1.368 (lit.)

bp

121-122 °C (lit.)

mp

−4 °C (lit.)

density

1.023 g/mL at 25 °C (lit.)

SMILES string

CO[Si](OC)(OC)OC

InChI

1S/C4H12O4Si/c1-5-9(6-2,7-3)8-4/h1-4H3

InChI key

LFQCEHFDDXELDD-UHFFFAOYSA-N

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Application

Tetramethyl orthosilicate (TMOS) is popularly used in the sol-gel synthesis of silicates1 and chromium-doped silicates and in the formation of hexagonal mesoporous silica layers.
Used in the sol-gel synthesis of chromium-doped silicates and in the formation of hexagonal mesoporous silica layers.

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 1 Inhalation - Eye Dam. 1 - Flam. Liq. 3 - Skin Irrit. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

78.8 °F - closed cup

Flash Point(C)

26 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Zian Lin et al.
Chemical communications (Cambridge, England), 47(34), 9675-9677 (2011-07-30)
An inorganic-organic hybrid affinity monolithic column was synthesized by a novel "one-pot" approach. The resulting hybrid affinity monoliths have potential applications in specific recognition and enrichment of glycoproteins.
Akhilesh Rai et al.
Langmuir : the ACS journal of surfaces and colloids, 26(6), 4152-4159 (2009-12-17)
We report an elegant and simple method to fabricate uniform silica films with controlled thickness, roughness, and hydrophilicity using nanogram quantities of silicatein, a protein involved in silica synthesis in sponges. The formation of uniform silica films was achieved by
Stephan Altmaier et al.
Journal of separation science, 31(14), 2551-2559 (2008-07-12)
Silica-based monolithic columns were prepared for HPLC with systematic variations of the tetramethoxysilane (TMOS) and polyethylene oxide (PEO) content as reactants in a sol-gel process accompanied by phase separation. The resulting monoliths showed differences in the macropore and silica skeleton
Carmen Carrasquilla et al.
Journal of the American Chemical Society, 134(26), 10998-11005 (2012-06-26)
Structure-switching, fluorescence-signaling DNA and RNA aptamers have been reported as highly versatile molecular recognition elements for biosensor development. While structure-switching DNA aptamers have been utilized for solid-phase sensing, equivalent RNA aptamers have yet to be successfully utilized in solid-phase sensors
Yan Fang et al.
Journal of chromatography. A, 1217(41), 6405-6412 (2010-09-03)
A simple capillary flow porometer (CFP) was assembled for through-pore structure characterization of monolithic capillary liquid chromatography columns in their original chromatographic forms. Determination of differential pressures and flow rates through dry and wet short capillary segments provided necessary information

Articles

Silica's versatility spans various industries, including biomedical applications.

Hybrid organic-inorganic sol-gel materials containing silica were first called “ORMOSILs” in 1984.

The properties of many devices are limited by the intrinsic properties of the materials that compose them.

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