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112801

Sigma-Aldrich

Pyridoxine hydrochloride

98%

Synonym(s):

Adermine hydrochloride, PN HCl, Pyridoxol hydrochloride, Vitamin B6 hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C8H11NO3 · HCl
CAS Number:
Molecular Weight:
205.64
Beilstein:
3632435
EC Number:
MDL number:
UNSPSC Code:
12352005
PubChem Substance ID:
Pricing and availability is not currently available.

Assay

98%

form

powder

color

white to off-white

mp

214-215 °C (lit.)

SMILES string

Cl[H].Cc1ncc(CO)c(CO)c1O

InChI

1S/C8H11NO3.ClH/c1-5-8(12)7(4-11)6(3-10)2-9-5;/h2,10-12H,3-4H2,1H3;1H

InChI key

ZUFQODAHGAHPFQ-UHFFFAOYSA-N

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General description

Pyridoxine hydrochloride is a water soluble vitamin. It is available through dietary sources like, meat, fish, nuts, vegetables and fruits.[1]

Biochem/physiol Actions

Pyridoxine/vitamin B6 is implicated in cellular metabolism, fatty acid biosynthesis, amino acid biosynthesis and catabolism. It is also implicated in the production of neurotransmitters, chlorophyll and plant hormones. Pyridoxine acts as a cofactor for several biochemical reactions.[2] Pyridoxine deficiency is associated with peripheral neuropathy.[3] Pyridoxine hydrochloride is available in parenteral and oral formulations.[1]

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Chapter 40 - Nutritional Deficiencies and Syndromes Associated with Alcoholism
Textbook of Clinical Neurology, 897-917 (2007)
Critical Care Toxicology: Diagnosis and Management of the Critically Poisoned Patient (2017)
Vitamin B6 and its role in cell metabolism and physiology
Parra M, et al.
Cells, 7(7), 84-84 (2018)
Manfred Eggersdorfer et al.
Angewandte Chemie (International ed. in English), 51(52), 12960-12990 (2012-12-05)
The discovery of vitamins as essential factors in the diet was a scientific breakthrough that changed the world. Diseases such as scurvy, rickets, beriberi, and pellagra were recognized to be curable with an adequate diet. These diseases had been prevalent
Vijay P Singh et al.
The Journal of organic chemistry, 78(4), 1478-1487 (2013-01-16)
Vitamin B6 is involved in a variety of enzymatic transformations. Some recent findings also indicate an antioxidant role of the vitamin in biological systems. We set out to turn pyridoxine (1a) into a catalytic chain-breaking and hydroperoxide-decomposing antioxidant by replacing

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