1602706

Ribavirin

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): 1-β-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide
• Empirical Formula (Hill Notation): C₈H₁₂N₄O₅
• CAS Number: 36791-04-5
• Molecular Weight: 244.20
• NACRES: NA.24
• PubChem Substance ID: 329751040
• UNSPSC Code: 41116107
• MDL number: MFCD00058564

Properties

• grade: pharmaceutical primary standard
• agency: USP
• API family: ribavirin
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: NC(=O)c1ncn(n1)[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O
• InChI: 1S/C8H12N4O5/c9-6(16)7-10-2-12(11-7)8-5(15)4(14)3(1-13)17-8/h2-5,8,13-15H,1H2,(H2,9,16)/t3-,4-,5-,8-/m1/s1
• InChI key: IWUCXVSUMQZMFG-AFCXAGJDSA-N
• Gene Information: human ... IMPDH1(3614)

Description

General description

Analog of the imidazole nucleotide intermediates in purine nucleotide biosynthesis.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Ribavirin USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Biochem/physiol Actions

Antiviral agent used against a wide variety of human viral infections, in particular, chronic hepatitis C, HIV, and adenovirus. Its metabolite, ribavirin 5′-phosphate, is an inhibitor of inosine monophosphate (IMP) dehydrogenase, but many other mechanisms of action are also supported with experimental evidence.

Antiviral agent used against a wide variety of human viral infections, in particular, chronic hepatitis C, HIV, and adenovirus. Its metabolite, ribavirin 5′-phosphate, is an inhibitor of inosine monophosphate (IMP) dehydrogenase.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• pictograms: GHS08
• signalword: Danger
• hcodes: H341,H360FD
• pcodes: P201 - P308 + P313
• Hazard Classifications: Muta. 2 - Repr. 1B
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable