V6879

[Lys⁸]-Vasopressin

≥98% (HPLC)

• Synonym(s): Lysine vasopressin, Lyspressin
• Empirical Formula (Hill Notation): C₄₆H₆₅N₁₃O₁₂S₂
• CAS Number: 50-57-7
• Molecular Weight: 1056.22
• NACRES: NA.32
• PubChem Substance ID: 24900764
• UNSPSC Code: 51111800
• EC Number: 200-050-5
• MDL number: MFCD00133970
• Form: powder
• Assay: ≥98% (HPLC)
• Biological source: synthetic (organic)

Properties

• biological source: synthetic (organic)
• Quality Segment: 200
• sterility: non-sterile
• assay: ≥98% (HPLC)
• form: powder
• solubility: 0.1 M acetic acid: 20 mg/mL, clear, colorless
• UniProt accession no.: P01185
• shipped in: ambient
• storage temp.: −20°C
• SMILES string: CC(O)=O.NCCCCC(NC(=O)C1CCCN1C(=O)C2CSSCC(N)C(=O)NC(Cc3ccc(O)cc3)C(=O)NC(Cc4ccccc4)C(=O)NC(CCC(N)=O)C(=O)NC(CC(N)=O)C(=O)N2)C(=O)NCC(N)=O
• InChI: 1S/C46H65N13O12S2.C2H4O2/c47-17-5-4-9-29(40(65)52-22-38(51)63)54-45(70)35-10-6-18-59(35)46(71)34-24-73-72-23-28(48)39(64)55-31(20-26-11-13-27(60)14-12-26)43(68)56-32(19-25-7-2-1-3-8-25)42(67)53-30(15-16-36(49)61)41(66)57-33(21-37(50)62)44(69)58-34;1-2(3)4/h1-3,7-8,11-14,28-35,60H,4-6,9-10,15-24,47-48H2,(H2,49,61)(H2,50,62)(H2,51,63)(H,52,65)(H,53,67)(H,54,70)(H,55,64)(H,56,68)(H,57,66)(H,58,69);1H3,(H,3,4)
• InChI key: NKWAIKZITYLOMT-UHFFFAOYSA-N
• Gene Information: human ... AVP(551)

Description

Application

[Lys⁸]-Vasopressin was used as a test compound in quantitative analysis of peptides and proteins by using on-line capillary isoelectric focusing-mass spectrometry.[1]The product was used for studying the coupling of a polymer-based microchip electrophoresis to MALDI-TOF MS by using rotating ball interface.[2]

Biochem/physiol Actions

Predominant form of vasopressin present in pigs and marsupials. It has lower vasopressor and antidiuretic activity than Arg⁸-vasopressin.

[Lys⁸]-Vasopressin also refers as Lysine vasopressin or Lyspressin is the predominant form of vasopressin present in pigs and marsupials. It antagonizes the amnesia in rats.[3] Lyspressin can also induce resistance to extinction of active avoidance behaviour.[4]

Preparation Note

2 mg of [Lys8]-Vasopressin dissolves in 0.1 mL, 0.1M HOAc to yield a clear, colorless solution.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves