SML0216

Brinzolamide

≥98% (HPLC)

• Synonym(s): (5R)-5-Ethylamino-3-(3-methoxypropyl)-2,2-dioxo-2?6,9-dithia-3-azabicyclo[4.3.0]nona-7,10-diene-8-sulfonamide, (R)- 4-(ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide, AL 4862
• Empirical Formula (Hill Notation): C₁₂H₂₁N₃O₅S₃
• CAS Number: 138890-62-7
• Molecular Weight: 383.51
• NACRES: NA.77
• PubChem Substance ID: 329825236
• UNSPSC Code: 12352200
• MDL number: MFCD08067749
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated

Properties

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: DMSO: ≥10 mg/mL
• storage temp.: −20°C
• SMILES string: CCN[C@H]1CN(CCCOC)S(=O)(=O)c2sc(cc12)S(N)(=O)=O
• InChI: 1S/C12H21N3O5S3/c1-3-14-10-8-15(5-4-6-20-2)23(18,19)12-9(10)7-11(21-12)22(13,16)17/h7,10,14H,3-6,8H2,1-2H3,(H2,13,16,17)/t10-/m0/s1
• InChI key: HCRKCZRJWPKOAR-JTQLQIEISA-N
• Gene Information: human ... CA2(760)

Description

General description

Brinzolamide is a small molecular weight compound that has an ability to bind melanin. This drug is used in ocular therapy.[1]

Application

Brinzolamide has been used as a melanin binding compound or drug in melanin binding assays.[1] It has also been used as a carbonic anhydrase inhibitor (CAI).

Biochem/physiol Actions

Brinzolamide is a carbonic anhydrase II inhibitor

Brinzolamide is a carbonic anhydrase II inhibitor used to lower intraocular pressure.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable