Skip to Content
Merck
All Photos(7)

Key Documents

View All Documentation

SAE0212

Sigma-Aldrich

Mucin Probe, StcE

Biotin and FLAG® tagged, powder

Synonym(s):

Catalytically inactive Mucin specific protease StcE

Sign Into View Organizational & Contract Pricing
All Photos(7)

About This Item

UNSPSC Code:
12352202
NACRES:
NA.77

Quality Level

200

form

powder

UniProt accession no.

O82882

shipped in

wet ice

storage temp.

-10 to -25°C

General description

Mucin Probe, StcE is a proteolytically inactive mutant (E447D) form of Mucinase StcE that maintains ability to tightly bind mucin proteins. The recombinant protein carries a 3XFLAG tag and is also enzymatically biotinylated at the C-term of the protein. While there are many applications, this product is designed to probe mucin dense tissues. It will non-covalently, and selectively bind to Mucin-domain glycoproteins with dense O-linked glycosylation. Secondary reporting tools can then be used to bind the probe using its FLAG® tag or Biotin conjugate.

Legal Information

FLAG is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Keira E Mahoney et al.
Current protocols, 4(7), e1100-e1100 (2024-07-10)
Mucin-domain glycoproteins are characterized by their high density of glycosylated serine and threonine residues, which complicates their analysis by mass spectrometry. The dense glycosylation renders the protein backbone inaccessible to workhorse proteases like trypsin, the vast heterogeneity of glycosylation often

Related Content

Cancer Research Modeling and Profiling Tools

Discover cancer research resources with modeling and profiling tools for cell culture, genomics, biomarkers, and more to help maximize your cancer research.

Cancer Research Modeling and Profiling Tools

Discover cancer research resources with modeling and profiling tools for cell culture, genomics, biomarkers, and more to help maximize your cancer research.

Cancer Research Modeling and Profiling Tools

Discover cancer research resources with modeling and profiling tools for cell culture, genomics, biomarkers, and more to help maximize your cancer research.

Cancer Research Modeling and Profiling Tools

Discover cancer research resources with modeling and profiling tools for cell culture, genomics, biomarkers, and more to help maximize your cancer research.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service