N9879
NADase from porcine brain
≥0.007 unit/mg solid
Synonym(s):
DPN Nucleosidase, NAD+ glycohydrolase
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About This Item
CAS Number:
MDL number:
UNSPSC Code:
12352204
NACRES:
NA.54
Recommended Products
form
powder
specific activity
≥0.007 unit/mg solid
solubility
insoluble
storage temp.
−20°C
General description
NADase is a glycohydrolase that catalyzes ADP-ribose transfer.
Application
NADase from porcine brain has been used in a study to investigate histidine and related compounds resulting from catalyzed ADP-riboslyation. It has also been used in a study to investigate the preparation of arylazide-substituted pyridine adenine dinucleotides for photoaffinity labeling.
Biochem/physiol Actions
Nicotinamide has been shown to inhibit NADase activity.
Unit Definition
One unit will hydrolyze 1.0 μmole of β-NAD to nicotinamide and ADP-ribose per min at pH 7.3 at 37 °C.
Physical form
Acetone-dried powder
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Nicholas Chiorazzi
Hematology. American Society of Hematology. Education Program, 2012, 76-87 (2012-12-13)
Several prognostic markers based on genetic, phenotypic, and molecular characteristics of chronic lymphocytic leukemia (CLL) B cells have emerged in the past decade. The clinical utility of these newer prognostic indicators, alone or in combination with each other and other
Preparation and Evaluation of Arylazide-Substituted Pyridine Adenine Dinucleotides for Photoaffinity Labeling Experiments
Liu, W., et al.
Photochemistry and Photobiology, 63, 793-799 (1996)
Shoko Nakayama et al.
Hematology (Amsterdam, Netherlands), 17(6), 317-320 (2012-11-22)
The accurate determination of cytoplasmic immunoglobulin (cIg) light chain (LC) expression is important to differentiate reactive plasmacytosis from a clonal plasma cell neoplasm such as plasma cell myeloma (PCM). Through retrospective analysis, we studied the cytoplasmic kappa/lambda ratio of CD38-positive
Julien Calvo et al.
PloS one, 7(11), e50495-e50495 (2012-12-05)
Hematopoietic stem cells are responsible for the generation of the entire blood system through life. This characteristic relies on their ability to self renew and on their multi-potentiality. Thus quantification of the number of hematopoietic stem cells in a given
K A Wall et al.
The Biochemical journal, 335 ( Pt 3), 631-636 (1998-10-31)
Carba-NAD and pseudocarba-NAD are carbocyclic analogues of NAD+ in which a 2,3-dihydroxycyclopentane methanol replaces the beta-d-ribonucleotide ring of the nicotinamide riboside moiety of NAD+ [Slama and Simmons (1988) Biochemistry 27, 183-193]. These carbocyclic NAD+ analogues, related to each other as
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