D8399

Danazol

≥98% (TLC), powder, androgen receptor agonist

• Synonym(s): 17β-Hydroxy-2,4,17α-pregnadien-20-yno[2,3-d]isoxazole, 2,4,17α-Pregnadien-20-yno[2,3-d]­isoxa­zol-17-ol
• Empirical Formula (Hill Notation): C₂₂H₂₇NO₂
• CAS Number: 17230-88-5
• Molecular Weight: 337.46
• EC Number: 241-270-1
• MDL number: MFCD00056838
• UNSPSC Code: 51111800
• PubChem Substance ID: 24277708
• NACRES: NA.77

Properties

• product name: Danazol, ≥98%
• Assay: ≥98%
• form: powder
• drug control: regulated under CDSA - not available from Sigma-Aldrich Canada
• originator: Sanofi Aventis
• SMILES string: CC12Cc3cnoc3C=C1CCC4C2CCC5(C)C4CC[C@@]5(O)C#C
• InChI: 1S/C22H27NO2/c1-4-22(24)10-8-18-16-6-5-15-11-19-14(13-23-25-19)12-20(15,2)17(16)7-9-21(18,22)3/h1,11,13,16-18,24H,5-10,12H2,2-3H3/t16?,17?,18?,20?,21?,22-/m0/s1
• InChI key: POZRVZJJTULAOH-ZIKCMSSPSA-N

Description

Biochem/physiol Actions

Danazol is a weak androgen; anterior pituitary suppressant.

Features and Benefits

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety Information

• Pictograms: GHS08,GHS07
• Signal Word: Warning
• Hazard Statements: H312 + H332,H361
• Precautionary Statements: P202 - P261 - P280 - P302 + P352 + P312 - P304 + P340 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Repr. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves