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Merck

D2004

4-(Dimethylamino)benzaldehyde

suitable for histochemical demonstration of nitro blue tetrazolium reduction in neutrophils

Synonym(s):

p-Dimethylaminobenzaldehyde, DMAB, Ehrlich’s reagent

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About This Item

Linear Formula:
(CH3)2NC6H4CHO
CAS Number:
100-10-7
Molecular Weight:
149.19
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
57654078
EC Number:
202-819-0
Beilstein/REAXYS Number:
606802
MDL number:
MFCD00003381

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Product Name

4-(Dimethylamino)benzaldehyde, suitable for histochemical demonstration of nitro blue tetrazolium reduction in neutrophils

Quality Level

200

InChI key

BGNGWHSBYQYVRX-UHFFFAOYSA-N

InChI

1S/C9H11NO/c1-10(2)9-5-3-8(7-11)4-6-9/h3-7H,1-2H3

SMILES string

CN(C)c1ccc(C=O)cc1

assay

≥99% (TLC)

form

powder

mp

72-75 °C (lit.)

solubility

ethanol: 50 mg/mL

suitability

suitable for histochemical demonstration of nitro blue tetrazolium reduction in neutrophils

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

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1 of 4

This Item
15647710976233130
4-(Dimethylamino)benzaldehyde suitable for histochemical demonstration of nitro blue tetrazolium reduction in neutrophils

Sigma-Aldrich

D2004

4-(Dimethylamino)benzaldehyde

4-(Dimethylamino)benzaldehyde ACS reagent, 99%

Sigma-Aldrich

156477

4-(Dimethylamino)benzaldehyde

4-(Dimethylamino)benzaldehyde 98%

Sigma-Aldrich

109762

4-(Dimethylamino)benzaldehyde

4-(Dimethylamino)benzaldehyde puriss. p.a., reag. Ph. Eur., ≥99% (perchloric acid titration)

Sigma-Aldrich

33130

4-(Dimethylamino)benzaldehyde

assay

≥99% (TLC)

assay

99%

assay

98%

assay

≥99% (perchloric acid titration)

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

200

solubility

ethanol: 50 mg/mL

solubility

alcohol: passes test (APHA ≤60), hydrochloric acid: passes test

solubility

H2O: slightly soluble

solubility

ethanol: 0.1 g/10 mL

storage temp.

room temp

storage temp.

-

storage temp.

-

storage temp.

-

form

powder

form

powder

form

solid

form

-

mp

72-75 °C (lit.)

mp

72-75 °C (lit.)

mp

72-75 °C (lit.)

mp

72-75 °C (lit.), 73-75 °C

Application

4-(Dimethylamino)benzaldehyde (DMAB or Ehrlich’s reagent) has been used as a color reagent for the determination of hydroxyproline level.[1]It forms colored condensation products (Schiff bases) with pyrroles and primary amines. DMAB is also suitable as a reagent to develop latent fingermarks on paper surfaces yielding impressions that are both colored and photoluminescent.
Forms colored condensation products (Schiff bases) with pyrroles and primary amines.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H317

Hazard Classifications

Skin Sens. 1B

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

327.2 °F - closed cup

flash_point_c

164 °C - closed cup

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
MKCX9766
MKCV4370
MKCR5178
MKCQ2980
MKCP8867

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Jamie Morrison et al.
The American journal of pathology, 166(6), 1701-1710 (2005-05-28)
Duchenne muscular dystrophy was initially described as a myosclerosis because of the conspicuous progression of interstitial fibrosis. Using the mdx mouse homologue, we have shown previously that the accumulation of intramuscular collagen is profoundly influenced by the presence or absence
C Creuzenet et al.
The Journal of biological chemistry, 275(45), 34873-34880 (2000-08-24)
FlaA1 is a small soluble protein of unknown function in Helicobacter pylori. It has homologues that are essential for the virulence of numerous medically relevant bacteria. FlaA1 was overexpressed as a histidine-tagged protein and purified to homogeneity by nickel chelation
Rosario Zamora et al.
Journal of agricultural and food chemistry, 52(13), 4166-4171 (2004-06-24)
The Ehrlich reaction was optimized to determine the formation of pyrrolized phospholipids in edible oils in an attempt to understand the color reversion produced during the deodorization of poorly degummed edible oils. The procedure consisted of the treatment of the
M Stefek et al.
Biochimica et biophysica acta, 1502(3), 398-404 (2000-11-09)
In the present work, pepsin digests of tail tendons from streptozotocin-diabetic rats were found to contain material that reacted rapidly at room temperature with p-dimethylaminobenzaldehyde (Ehrlich's reagent) to give an adduct with an absorbance spectrum characteristic of the Ehrlich chromogen
Jun-Min Guo et al.
Journal of agricultural and food chemistry, 58(11), 6556-6561 (2010-05-15)
A simple colorimetric method for the differentiation of indoleacetic acid (IAA) and indolebutyric acid (IBA) in plant samples is described. The color change is based upon the reaction between the auxins and p-(dimethylamino)benzaldehyde (PDAB, Ehrlich reagent) following the electrophilic substitution
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