D047

(±)-SKF-38393 hydrochloride

crystalline, ≥98% (HPLC)

• Synonym(s): (±)-1-Phenyl-2,3,4,5-tetrahydro-(1H)-3-benzazepine-7,8-diol hydrochloride
• Empirical Formula (Hill Notation): C₁₆H₁₇NO₂ · HCl
• CAS Number: 62717-42-4
• Molecular Weight: 291.77
• MDL number: MFCD00069248
• UNSPSC Code: 12352200
• PubChem Substance ID: 24277907
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: crystalline
• storage condition: desiccated; protect from light
• color: white
• solubility: H₂O: >5 mg/mL; aqueous base: soluble (unstable)
• SMILES string: Cl.Oc1cc2CCNCC(c3ccccc3)c2cc1O
• InChI: 1S/C16H17NO2.ClH/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11;/h1-5,8-9,14,17-19H,6-7,10H2;1H
• InChI key: YEWHJCLOUYPAOH-UHFFFAOYSA-N
• Gene Information: human ... DRD1(1812)

Description

Application

(±)-SKF-38393 hydrochloride has been used as a selective D1 receptor agonist as a part of dopaminergic treatment. It has also been used to study its effect on prolactin in male baboons.

Biochem/physiol Actions

(±)-SKF-38393 is a D1 dopamine receptor agonist. It is known to promote the production of glutamate in the hippocampus.

Caution

This material is hygroscopic. Air-sensitive. Light-sensitive.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves