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B2517

6-Biopterin

≥97%

Synonym(s):

(1’R,2’S)-Biopterin, 2-Amino-4-hydroxy-6-(1,2-dihydroxypropyl)pteridine, L-erythro-6-(1,2-Dihydroxypropyl)pterin

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About This Item

Empirical Formula (Hill Notation):
C9H11N5O3
CAS Number:
22150-76-1
Molecular Weight:
237.22
UNSPSC Code:
41106305
NACRES:
NA.51
PubChem Substance ID:
24891654
EC Number:
244-807-8
Beilstein/REAXYS Number:
87860
MDL number:
MFCD00036787
Form:
powder
Assay:
≥97%
Solubility:
1 M NaOH: soluble-10 mg/mL, clear, colorless to light greenish-yellow
Biological source:
synthetic
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biological source

synthetic

Quality Segment

200

assay

≥97%

form

powder

solubility

1 M NaOH: soluble-10 mg/mL, clear, colorless to light greenish-yellow

storage temp.

2-8°C

SMILES string

C[C@H](O)[C@H](O)c1cnc2NC(N)=NC(=O)c2n1

InChI

1S/C9H11N5O3/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7/h2-3,6,15-16H,1H3,(H3,10,11,13,14,17)/t3-,6-/m0/s1

InChI key

LHQIJBMDNUYRAM-DZSWIPIPSA-N

Application

6-Biopterin is an oxidation product from the melanogenesis regulating cofactor (6R)5,6,7,8 tetrahydrobiopterin (6-BH4). In vitro, 6-Biopterin is cytotoxic to melanocytes. However, in vivo, 6-Biopterin is rapidly and sequentially reduced back to 6-GH4 via q-BH2. Recent studies suggest that 6-Biopterin among other pteridines may be a useful non-invasive biomarker for cancer.

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This Item
3727219565SML0675
6-Biopterin ≥97%

Sigma-Aldrich

B2517

6-Biopterin

7,8-Dihydro-L-biopterin ≥94% (HPLC)

Sigma-Aldrich

37272

7,8-Dihydro-L-biopterin

(6S)-5,6,7,8-Tetrahydro-L-erythro-biopterin sulfate ≥96% (HPLC)

Sigma-Aldrich

19565

(6S)-5,6,7,8-Tetrahydro-L-erythro-biopterin sulfate

α-Methylnorepinephrine ≥95% (HPLC)

Sigma-Aldrich

SML0675

α-Methylnorepinephrine

solubility

1 M NaOH: soluble-10 mg/mL, clear, colorless to light greenish-yellow

solubility

-

solubility

-

solubility

DMSO: 5 mg/mL, clear (warmed)

assay

≥97%

assay

≥94% (HPLC)

assay

≥96% (HPLC)

assay

≥95% (HPLC)

biological source

synthetic

biological source

-

biological source

-

biological source

-

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

form

powder

form

-

form

powder or crystals

form

powder

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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