A2536

L-2-Aminobutyric acid

BioReagent, suitable for cell culture

• Synonym(s): L-α-Aminobutyric acid
• Empirical Formula (Hill Notation): C₄H₉NO₂
• CAS Number: 1492-24-6
• Molecular Weight: 103.12
• UNSPSC Code: 12352205
• NACRES: NA.75
• PubChem Substance ID: 24890666
• EC Number: 216-083-3
• Beilstein/REAXYS Number: 1720935
• MDL number: MFCD00064415

Properties

• Quality Segment: 200
• biological source: Porcine kidney, microbial, plant
• product line: BioReagent
• form: powder
• technique(s): cell culture | mammalian: suitable
• solubility: water: 50 mg/mL, clear, colorless
• shipped in: ambient
• storage temp.: room temp
• SMILES string: CC[C@H](N)C(O)=O
• InChI: 1S/C4H9NO2/c1-2-3(5)4(6)7/h3H,2,5H2,1H3,(H,6,7)/t3-/m0/s1
• InChI key: QWCKQJZIFLGMSD-VKHMYHEASA-N

Description

General description

L-2-Aminobutyric acid is synthesized from L-threonine and L-aspartic acid through a ⍺-transamination reaction. It is an L-alanine analogue with an ethyl side chain.

Biochem/physiol Actions

L-α-Aminobutyric acid (AABA) is an isomer of the non-natural amino acid aminobutyric acid with activity in the γ-glutamyl cycle that regulates glutathione biosynthesis. Recently AABA has been studied as a supplement to in vitro maturation medium (NCSU 23 medium) for culture of oozytes and embryos. This product has been qualified for use in cell culture. AABA is also used as a substitute amino acid for alanine in studies on peptide function.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H317
• pcodes: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Hazard Classifications: Skin Sens. 1
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves