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Y0000538

Dexamethasone isonicotinate

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Dexamethasone 21-isonicotinate

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About This Item

Empirical Formula (Hill Notation):
C28H32FNO6
CAS Number:
Molecular Weight:
497.56
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

dexamethasone

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C28H32FNO6/c1-16-12-21-20-5-4-18-13-19(31)6-9-25(18,2)27(20,29)22(32)14-26(21,3)28(16,35)23(33)15-36-24(34)17-7-10-30-11-8-17/h6-11,13,16,20-22,32,35H,4-5,12,14-15H2,1-3H3/t16-,20+,21+,22+,25+,26+,27+,28+/m1/s1

InChI key

BQTXJHAJMDGOFI-NJLPOHDGSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Dexamethasone isonicotinate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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A C Moreira et al.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 24(7), 339-341 (1992-07-01)
A previous study in an untreated girl with 17 alpha-hydroxylase deficiency syndrome (17-OHDS) indicated that in the absence of cortisol production, ACTH and corticosterone (B) may interact to modulate the brain-pituitary-adrenocortical system. The ACTH-B interplay was further examined in this
Jorge Elizondo-Rodriguez et al.
Foot & ankle international, 34(1), 8-14 (2013-02-07)
The objective of this study was to compare intramuscularly applied botulinum toxin A (BTX-A) in the gastroc-soleus complex with intralesional steroids for the treatment of plantar fasciitis. The patients were randomly divided into 2 groups according to the treatment received.
Thomas Wittek et al.
Berliner und Munchener tierarztliche Wochenschrift, 118(3-4), 140-149 (2005-04-05)
The objective of the study was to describe the effects of a short acting glucocorticoid which was administered immediately after parturition in dairy cows on haematological, immunologic and metabolic parameters. The study was performed on 104 cows, 52 cows received
N E Robinson et al.
Equine veterinary journal, 34(1), 17-22 (2002-01-31)
This study used a cross-over design to compare the efficacy of 3 corticosteroids for the relief of airway obstruction and inflammation in 9 heaves-affected horses. The severity of airway obstruction and inflammation was quantified by measurement of lung function and
P L Toutain et al.
Journal of veterinary pharmacology and therapeutics, 5(1), 33-43 (1982-03-01)
The pharmacokinetics of Dexamethasone (DXM) was studied in four cows all of which received DXM alcohol and DXM 21 isonicotinate (as a solution) by the intravenous and intramuscular routes. Concentrations of DXM and cortisol were determined using high performance liquid

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