Skip to Content
Merck
All Photos(3)

Documents

S6387

Sigma-Aldrich

Sulfadiazine sodium salt

≥98% (HPLC)

Synonym(s):

4-Amino-N-(2-pyrimidinyl)benzenesulfonamide sodium salt, SPS Agar Supplement

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C10H9N4NaO2S
CAS Number:
Molecular Weight:
272.26
Beilstein:
4068213
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

Assay

≥98% (HPLC)

form

crystalline powder

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

SMILES string

Nc1ccc(cc1)S(=O)(=O)N([Na])c2ncccn2

InChI

1S/C10H9N4O2S.Na/c11-8-2-4-9(5-3-8)17(15,16)14-10-12-6-1-7-13-10;/h1-7H,11H2;/q-1;+1

InChI key

JLDCNMJPBBKAHH-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

Sulfadiazine sodium salt is a broad-spectrum antibiotic belonging to the class of sulfonamides commonly used against gram-postive and gram-negative microorganisms in humans and veterinary medication. Its mode of action involves inhibiting the multiplication of bacteria as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Sulfadiazine may be used as an internal standard for the determination of sulfapyridine in biological samples using high-performance liquid chromatography technique.

Pictograms

Exclamation markEnvironment

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Chun-Xue Zhou et al.
Antimicrobial agents and chemotherapy, 63(10) (2019-08-07)
In this study, we analyzed the global metabolomic changes associated with Toxoplasma gondii infection in mice in the presence or absence of sulfadiazine sodium (SDZ) treatment. BALB/c mice were infected with T. gondii GT1 strain and treated orally with SDZ
Eco-toxic effects of sulfadiazine sodium, sulfamonomethoxine sodium and enrofloxacin on wheat, Chinese cabbage and tomato
Ecotoxicology (London, England), 18(7), 878-885 (2009)
High-performance liquid chromatographic method for determination of sulfapyridine in human saliva using post-column, in-line derivatization with fluorescamine
Sista.S.H, et al.
Journal of Chromatography. B, Biomedical Applications, 273(2), 103-106 (1983)
Drugs: Synonyms and Properties (2017)
G G Bruer et al.
BMC veterinary research, 15(1), 55-55 (2019-02-13)
H1 receptor antagonists are commonly used for the treatment of allergic diseases. The aim of this study was to find out, if antihistaminic compounds like mepyramine have the ability to influence the activity of antibacterials. Therefore, the checkerboard method was

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service