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Key Documents

8.03127

Sigma-Aldrich

Diethylene glycol monoethyl ether

for synthesis

Synonym(s):

Diethylene glycol monoethyl ether, Carbitol, 2-(2-Ethoxyethoxy)-ethanol, Ethyl diglycol

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About This Item

Empirical Formula (Hill Notation):
C6H14O3
CAS Number:
Molecular Weight:
134.17
MDL number:
UNSPSC Code:
12352104
EC Index Number:
203-919-7
NACRES:
NA.22

vapor pressure

0.13 hPa ( 20 °C)

Quality Level

Assay

≥98% (GC)

form

liquid

autoignition temp.

204 °C

potency

5900-6100 mg/kg LD50, oral (Rat)
8476 mg/kg LD50, skin (Rabbit)

expl. lim.

1.8-12.2 % (v/v)

bp

202 °C/1013 hPa

mp

-78 °C

transition temp

flash point 94 °C

density

0.99 g/cm3 at 20 °C

storage temp.

2-30°C

InChI

1S/C6H14O3/c1-2-8-5-6-9-4-3-7/h7H,2-6H2,1H3

InChI key

XXJWXESWEXIICW-UHFFFAOYSA-N

Application


  • Investigation of piroctone olamine delivery to the skin from single, binary and ternary solvent systems: This study explores the efficacy of diethylene glycol monoethyl ether as a solvent in dermatological applications, highlighting its role in enhancing skin absorption properties, which is crucial for cosmetic and pharmaceutical formulations (Tang CF, et al., 2023).

  • Review of Pharmaceutical Applications of Diethylene Glycol Monoethyl Ether: This review comprehensively covers the pharmaceutical applications of diethylene glycol monoethyl ether, focusing on its solvent properties and roles in drug delivery systems, crucial for advancing drug formulation techniques (Hashemzadeh N, Jouyban A, 2022).
  • Stepwise Access of Emissive Ir(III) Complexes Bearing a Multi-Dentate Heteroaromatic Chelate: Demonstrates the application of diethylene glycol monoethyl ether in the synthesis of luminescent materials, providing valuable insights for the development of optical and electronic devices in material science (Zheng Z, et al., 2022).

Analysis Note

Assay (GC, area%): ≥ 98.0 % (a/a)
Density (d 20 °C/ 4 °C): 0.987 - 0.990
Water (K. F.): ≤ 0.20 %
Peroxide (as H₂O₂): ≤ 0.05 %
Identity (IR): passes test

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

204.8 °F - closed cup

Flash Point(C)

96 °C - closed cup


Certificates of Analysis (COA)

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