V-016

Nicotinamide (Vitamin B3) solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Synonym(s): Nicotinamide, Vitamin B₃, Niacinamide, Nicotinic acid amide, Pyridine-3-carboxylic acid amide, Vitamin PP
• Empirical Formula (Hill Notation): C₆H₆N₂O
• CAS Number: 98-92-0
• Molecular Weight: 122.12
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329828959
• EC Number: 200-659-6
• Beilstein/REAXYS Number: 383619
• MDL number: MFCD00006395

Properties

• grade: certified reference material
• Quality Segment: 300
• form: liquid
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• concentration: 1.0 mg/mL in methanol
• technique(s): gas chromatography (GC): suitable, liquid chromatography (LC): suitable
• mp: 128-131 °C (lit.)
• application(s): clinical testing
• format: single component solution
• storage temp.: −20°C
• SMILES string: NC(=O)c1cccnc1
• InChI: 1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)
• InChI key: DFPAKSUCGFBDDF-UHFFFAOYSA-N

Description

General description

Nicotinamide is also known as niacinamide or nicotinic acid amide. It is the water-soluble form of Vitamin B₃ found in plant and animal foods and mostly used as a dietary supplement.

Application

This certified solution standard is suitable for a variety of testing applications including quality control testing by HPLC for pharmaceutical preparations or dietary supplements.
Nicotinamide may be used as an analytical reference standard for the determination of the analyte in energy drinks by planar chromatography-multiple detection with confirmation by electrospray ionization mass spectrometry and in pharmaceutical formulations, by UV-visible spectrophotometry and multivariate analysis.

Biochem/physiol Actions

Nicotinamide is an amide derivative of vitamin B3 and a PARP inhibitor

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS02,GHS06,GHS08
• signalword: Danger
• hcodes: H225,H301 + H311 + H331,H370
• pcodes: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• target_organs: Eyes
• Storage Class: 3 - Flammable liquids
• wgk: WGK 2
• flash_point_f: 49.5 °F - closed cup
• flash_point_c: 9.7 °C - closed cup