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913650

Sigma-Aldrich

Polyoxyethylene bis(azide) solution

average Mn 450, 0.1 g/mL in THF

Synonym(s):

O,O′-Bis(2-azidoethyl)polyethylene glycol, PEG-diazide

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About This Item

Linear Formula:
N3(C2H4O)nC2H4N3
UNSPSC Code:
12352125
NACRES:
NA.23

form

liquid

Quality Level

100

mol wt

PEG ~400 Da
average Mn 450

concentration

0.1 g/mL in THF

color

pale yellow

storage temp.

2-8°C

Related Categories

Application

PEG for cross-linking and used in "click" chemistry reactions. PEGylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of PEG improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. Polymer for preparing enzyme conjugates soluble in organic solvents; promising drug carrier.

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

Target Organs

Central nervous system, Respiratory system

Supplementary Hazards

EUH018,EUH019

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

0.5 °F

Flash Point(C)

-17.5 °C

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Improving the tensile strength of carbon nanotube yarn via one-step double [2+1] cycloadditions.
H Kim, et al.
Korean Journal of Chemical Engineering, 33(1), 299-304 (2016)
Shao Qiong Liu et al.
Biomaterials, 30(8), 1453-1461 (2008-12-23)
In this study, biodegradable PEG-peptide hydrogels have been synthesized using Click chemistry. A series of Arg-Gly-Asp (RGD) containing peptides were prepared via a solid phase synthesis approach, which were further functionalized with azide to yield peptide azide or peptide diazide.
Tilman Läppchen et al.
European journal of medicinal chemistry, 89, 279-295 (2014-12-03)
Calixarene 0118 is a potent anti-angiogenic agent that effectively inhibited tumor growth in preclinical studies, and is currently being evaluated in a phase I clinical trial. We have designed two close mimetics of calixarene 0118 containing a terminal alkynyl-functional group

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