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Sigma-Aldrich

Nicotinamide-(amide-15N)

98 atom % 15N, 98% (CP)

Synonym(s):

3-Pyridine(carboxamide-15N), Vitamin B3-(amide-15N)

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About This Item

Empirical Formula (Hill Notation):
C6H615NNO
CAS Number:
113950-01-9
Molecular Weight:
123.12
MDL number:
MFCD00190532
UNSPSC Code:
12352202
PubChem Substance ID:
24881367

isotopic purity

98 atom % 15N

Quality Level

200

Assay

98% (CP)

form

solid

technique(s)

mass spectrometry (MS): suitable

color

white

mp

130-132 °C (lit.)

mass shift

M+1

SMILES string

[15NH2]C(=O)c1cccnc1

InChI

1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)/i7+1

InChI key

DFPAKSUCGFBDDF-CDYZYAPPSA-N

General description

Nicotinamide (or niacinamide) is an amide form of vitamin B3/nicotinic acid that can be used in a variety of cosmetic and pharmaceutical applications. It is found in meat, fish, nuts, and mushrooms, as well as in some vegetables. It is also a precursor for essential coenzymes.

Application

Nicotinamide-(amide-15N) can be utilized in the biosynthesis of nicotinamide adenine dinucleotide (NAD). This product can also be used as an analytical standard.

Packaging

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

302.0 °F - closed cup

Flash Point(C)

150 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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A review of nicotinamide: treatment of skin diseases and potential side effects
Rolfe HM
Journal of Cosmetic Dermatology, 13(4), 324-328 (2014)
Safety of high-dose nicotinamide: a review
Knip M, et al.
Diabetologia, 43(11), 1337-1345 (2000)
Igor Shats et al.
Cell metabolism, 31(3), 564-579 (2020-03-05)
Nicotinamide adenine dinucleotide (NAD), a cofactor for hundreds of metabolic reactions in all cell types, plays an essential role in metabolism, DNA repair, and aging. However, how NAD metabolism is impacted by the environment remains unclear. Here, we report an
Rong Grace Zhai et al.
Cellular and molecular life sciences : CMLS, 66(17), 2805-2818 (2009-05-19)
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase (NMNAT) has long been known as the master enzyme in NAD biosynthesis in living organisms. A burst of investigations on NMNAT, going beyond enzymology, have paralleled increasing discoveries of key roles played by NAD homeostasis in

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