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840054C

Avanti

Soy PC

Avanti Research™ - A Croda Brand 840054C

Synonym(s):

L-α-phosphatidylcholine (Soy)

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About This Item

CAS Number:
97281-47-5
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (840054C-25mg)
pkg of 2 × 4 mL (840054C-200mg)
pkg of 5 × 4 mL (840054C-500mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 840054C

concentration

10 mg/mL (840054C-25mg)
25 mg/mL (840054C-200mg)
25 mg/mL (840054C-500mg)

lipid type

phosphoglycerides
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)=O

InChI

1S/C42H80NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h14,16,20-21,40H,6-13,15,17-19,22-39H2,1-5H3/b16-14-,21-20-/t40-/m1/s1

InChI key

JLPULHDHAOZNQI-ZTIMHPMXSA-N

General description

L-α-phosphatidylcholine (Soy) is a naturally occurring phospholipid and the most abundant phospholipid in eukaryotic cellular membrane with high amount of PUFAs.

Application

Soy PC may be used for the synthesis of proteoliposomes, lipoprotein particle (LLP) mimics and flexible liposome (FLUV).

Biochem/physiol Actions

L-α-phosphatidylcholine plays an important role in the formation of liposomes. It is also used in small unilamellar vesicles (SUVs) synthesis.

Packaging

5 mL Clear Glass Sealed Ampule (840054C-200mg)
5 mL Clear Glass Sealed Ampule (840054C-25mg)
5 mL Clear Glass Sealed Ampule (840054C-500mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

Target Organs

Liver,Kidney, Respiratory system

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Piezo1 Channels Are Inherently Mechanosensitive
Syeda R, et al.
Testing, 17(7), 1739-1746 (2016)
Membrane curvature recognition by C reactive protein using lipoprotein mimics
Wang MS, et al.
Soft Matter, 8(30), 7909-7918 (2012)
Louiza Bohn Thomsen et al.
Materials (Basel, Switzerland), 12(21) (2019-11-07)
Magnetic nanoparticles have great prospects for drug delivery purposes, as they can be designed with various surface coatings and conjugated with drugs and targeting moieties. They also have a unique potential for precise delivery when guided by magnetic force. The
Superresolution and fluorescence dynamics evidence reveal that intact liposomes do not cross the human skin barrier.
Dreier J, et al.
PLoS ONE, 11(1), e0146514-e0146514 (2016)
Jes Dreier et al.
PloS one, 11(1), e0146514-e0146514 (2016-01-12)
In this study we use the combination of super resolution optical microscopy and raster image correlation spectroscopy (RICS) to study the mechanism of action of liposomes as transdermal drug delivery systems in human skin. Two different compositions of liposomes were
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