W355690
Isopropyl myristate
≥98%
Synonym(s):
Isopropyl tetradecanoate, Myristic acid isopropyl ester
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About This Item
Linear Formula:
CH3(CH2)12COOCH(CH3)2
CAS Number:
Molecular Weight:
270.45
FEMA Number:
3556
Beilstein:
1781127
EC Number:
Council of Europe no.:
386
MDL number:
UNSPSC Code:
12164502
PubChem Substance ID:
Flavis number:
9.105
NACRES:
NA.21
Recommended Products
biological source
synthetic
Quality Level
grade
Fragrance grade
Halal
Kosher
Agency
follows IFRA guidelines
reg. compliance
EU Regulation 1223/2009
Assay
≥98%
refractive index
n20/D 1.434 (lit.)
bp
193 °C/20 mmHg (lit.)
mp
~3 °C (lit.)
density
0.85 g/mL at 25 °C (lit.)
application(s)
flavors and fragrances
Documentation
see Safety & Documentation for available documents
food allergen
no known allergens
fragrance allergen
no known allergens
Organoleptic
faint; fatty; oily
SMILES string
CCCCCCCCCCCCCC(=O)OC(C)C
InChI
1S/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3
InChI key
AXISYYRBXTVTFY-UHFFFAOYSA-N
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General description
Isopropyl myristate is mainly used as a solubilizer, emulsifier and emollient in cosmetic and topical medicines. It is also used as a flavoring agent in the food industry.
Application
- Development of Nanostructured Lipid Carrier-Loaded Flavonoid-Enriched Zingiber officinale.: This research develops nanostructured lipid carriers for flavonoids derived from Zingiber officinale, employing Isopropyl myristate to stabilize these carriers and improve bioactive compound delivery (Shazwani SS et al., 2024).
- Comparative evaluation of physical and chemical enhancement techniques for transdermal delivery of linagliptin.: The study compares various enhancement methods for transdermal drug delivery, including the use of Isopropyl myristate, highlighting its effectiveness in permeation enhancement techniques (Karve T et al., 2024).
- Optimization of Conditions of Zanthoxylum Alkylamides Liposomes by Response Surface Methodology and the Absorption Characteristics of Liposomes in the Caco-2 Cell Monolayer Model.: This research optimizes liposome formulations containing Zanthoxylum alkylamides, with Isopropyl myristate being crucial in liposome stability and absorption characteristics (Wang R et al., 2024).
Biochem/physiol Actions
Odor at 1.0%
Taste at 10 ppm
Disclaimer
For R&D or non-EU Food use. Not for retail sale.
Storage Class Code
10 - Combustible liquids
WGK
awg
Flash Point(F)
>302.0 °F
Flash Point(C)
> 150 °C
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Handbook of Preservatives, 425-425 (2004)
Qian Zhang et al.
Pharmaceutical research, 30(1), 32-40 (2012-08-28)
In principle, maximum transepidermal fluxes of solutes should be similar for different vehicles, except when the solute or vehicle modifies the skin. Here we estimated maximum flux, stratum corneum solubility, diffusivity and permeability coefficient for a range of similarly sized
Fan Yang et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 82(1), 158-163 (2012-06-21)
Transdermal delivery of methotrexate (MTX) was investigated by using the solid-in-oil (S/O) technique. Because MTX was coated with nonionic surfactant molecules, the resulting complex was easy to dissolve in various organic solvents and provided a transparent solution in isopropyl myristate
Ji Zhang et al.
International journal of pharmaceutics, 421(1), 34-44 (2011-10-01)
In this study, microemulsion microstructures, key formulation variables, and their relationship to drug transdermal permeation enhancement were investigated. A microemulsion system with high water soluble capacity was developed, using isopropyl myristate, Labrasol, and Cremophor EL as oil, surfactant, and co-surfactant
Rajbharan Yadav et al.
Antimicrobial agents and chemotherapy, 59(4), 2286-2298 (2015-02-04)
Acinetobacter baumannii is among the most dangerous pathogens and emergence of resistance is highly problematic. Our objective was to identify and rationally optimize β-lactam-plus-aminoglycoside combinations via novel mechanism-based modeling that synergistically kill and prevent resistance of carbapenem-resistant A. baumannii. We
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