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ALD01654

Sigma-Aldrich

3-((2-methoxypyridin-3-yl) amino)-3-methylbutan-1-ol

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About This Item

UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

form

liquid

storage temp.

2-8°C

SMILES string

CC(CCO)(C)NC1=CC=CN=C1OC

InChI

1S/C11H18N2O2/c1-11(2,6-8-14)13-9-5-4-7-12-10(9)15-3/h4-5,7,13-14H,6,8H2,1-3H3

InChI key

DORIBENRPNIVDI-UHFFFAOYSA-N

Application

Traditionally challenging to access, this hindered amine provides a chemically differentiated building block for organic synthesis and medicinal chemistry, specifically for preparation of drug candidates containing hindered amine motifs. Additionally, this and over 80 other sterically hindered secondary amines in the Sigma-Aldrich portfolio provide structurally distinct screening compounds. Screen several through Aldrich Market Select. This hindered amine was accessed via a recent publication reported by Baran and coworkers using an innovative hydroamination method.

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Product No.
Description
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Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Related Content

The Baran Group works with Sigma-Aldrich in providing a portfolio of zinc-based reagents promoting difluoromethylation, trifluoromethylation, trifluoroethylation and isopropylation of aryl and heteroaryl motifs. Baran’s lab has also helped introduce a portable desaturase (Tz0Cl), which promotes the installation of alcohol and amine groups and leaves behind a highly useful tosyl group for further transformations.

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