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Quality Level
Assay
99%
mp
55-60 °C (lit.)
SMILES string
O=C1C=COc2ccccc12
InChI
1S/C9H6O2/c10-8-5-6-11-9-4-2-1-3-7(8)9/h1-6H
InChI key
OTAFHZMPRISVEM-UHFFFAOYSA-N
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General description
The compounds with chromone skeleton exhibits antiradical activities that provide protection against oxidative stress.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Pharmaceutics, 11(7) (2019-07-25)
The current pharmacological treatments for Parkinson's disease only offer symptomatic relief to the patients and are based on the administration of levodopa and catechol-O-methyltransferase or monoamine oxidase-B inhibitors (IMAO-B). Since the majority of drug candidates fail in pre- and clinical
Bioorganic & medicinal chemistry, 15(8), 2952-2962 (2007-02-27)
The interaction between leukocytes and the vascular endothelial cells (EC) via cellular adhesion molecules plays an important role in various inflammatory and immune diseases. The molecules that block these interactions have been targeted as potential therapeutic targets for acute and
Bioorganic & medicinal chemistry, 18(12), 4195-4201 (2010-06-18)
Human noroviruses (NoV) are now recognized as the most frequent cause of outbreaks and sporadic cases of acute gastroenteritis. Despite the significant economic impact and considerable morbidity of norovirus disease, no drug or vaccine is currently available to treat or
PloS one, 15(8), e0229477-e0229477 (2020-08-22)
The research was conducted in the "logical series" of seven ligands: chromone, flavone, 3-hydroxyflavone, 3,7-dihydroxyflavone, galangin, kaempferol and quercetin. Each subsequent ligand differs from the previous one, among others by an additional hydroxyl group. The studied chromone derivatives are plant
Effects of metformin on proliferation and apoptosis of human megakaryoblastic Dami and MEG-01 cells.
Journal of pharmacological sciences, 135(1), 14-21 (2017-09-21)
Metformin has received increasing attention for its potential anticancer activity against certain human leukemia cells, but its effects on human megakaryoblastic cells are unclear. This study aimed to investigate the effects of metformin on proliferation and apoptosis of human megakaryoblastic
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