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GS500

Sigma-Aldrich

Giemsa Stain, Modified

Synonym(s):

Giemsa Solution

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About This Item

MDL number:
MFCD00081642
UNSPSC Code:
41116121
PubChem Substance ID:
24895392
NACRES:
NA.47

form

solution

shelf life

Expiry date on the label.

IVD

for in vitro diagnostic use

concentration

0.4 % (w/v) in buffered methanol solution, pH 6.8, with stabilizers

pH

6.75-6.95

application(s)

hematology
histology

storage temp.

room temp

SMILES string

[Cl-].CN(C)c1ccc2N=C3C=CC(=[NH2+])C=C3Sc2c1

InChI

1S/C14H13N3S.ClH/c1-17(2)10-4-6-12-14(8-10)18-13-7-9(15)3-5-11(13)16-12;/h3-8,15H,1-2H3;1H

InChI key

NALREUIWICQLPS-UHFFFAOYSA-N

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Application

When blood films are stained using Giemsa Stain, the nucleus and cytoplasm of white blood cells take on characteristic blue or pink coloration. The use of purified eosin and thiazine dyes minimizes lot-to-lot variation.

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Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

51.8 °F - closed cup

Flash Point(C)

11 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Histophatologic Techniques (2006)
Cell Migration (2005)
Jing Zhang et al.
Cell death & disease, 11(7), 602-602 (2020-08-01)
Glioblastoma multiforme (GBM) is the most malignant primary brain tumor and has the highest mortality rate among cancers and high resistance to radiation and cytotoxic chemotherapy. Although some targeted therapies can partially inhibit oncogenic mutation-driven proliferation of GBM cells, therapies
The Giemsa stain: its history and applications
Barcia, et al,
International Journal of Surgical Pathology, 15(3) (2007)
Liat Peretz et al.
Scientific reports, 8(1), 93-93 (2018-01-10)
Inhibition of genes is a powerful approach to study their function. While RNA interference is a widely used method to achieve this goal, mounting evidence indicates that such an approach is prone to off-target effects. An alternative approach to gene
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