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40543

Supelco

(±)-Propranolol hydrochloride

analytical standard

Synonym(s):

(±)-1-Isopropylamino-3-(1-naphthyloxy)-2-propanol hydrochloride, DL-Propranolol hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C16H21NO2 · HCl
CAS Number:
318-98-9
Molecular Weight:
295.80
Beilstein:
4164259
EC Number:
206-268-7
MDL number:
MFCD00012558
UNSPSC Code:
41116107
PubChem Substance ID:
329756000
NACRES:
NA.24

grade

analytical standard

Quality Level

100

Assay

≥98.5% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

impurities

≤1.0% water

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Cl.CC(C)NCC(O)COc1cccc2ccccc12

InChI

1S/C16H21NO2.ClH/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16;/h3-9,12,14,17-18H,10-11H2,1-2H3;1H

InChI key

ZMRUPTIKESYGQW-UHFFFAOYSA-N

Gene Information

human ... ADRB1(153) , ADRB2(154)

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM1814
BCCL3999
BCCH5806
BCCF4034
BCCD0212

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Pawel Szychta et al.
Plastic and reconstructive surgery, 133(4), 852-862 (2013-12-20)
Infantile hemangioma is a vascular tumor and requires treatment in lesions manifested by potentially dangerous symptoms. Several publications have reported that involution of infantile hemangioma could be accelerated by propranolol but have used only invalidated subjective measures of assessment. The
Dennis D Rasmussen et al.
Alcoholism, clinical and experimental research, 38(6), 1532-1539 (2014-06-04)
Evidence suggests that activation of the noradrenergic system may contribute to alcohol drinking in animals and humans. Our previous studies demonstrated that blocking α1 -adrenergic receptors with the antagonist, prazosin, decreased alcohol drinking in rats under various conditions. As noradrenergic
Katherine B Püttgen
Pediatric clinics of North America, 61(2), 383-402 (2014-03-19)
Propranolol has replaced corticosteroids as preferred first-line therapy for the management of infantile hemangiomas (IH). The topical β-blocker timolol is now an alternative to oral propranolol and watchful waiting for smaller IH. Research in the last decade has provided evidence-based
Canan Akyüz et al.
Pediatric blood & cancer, 61(5), 931-932 (2013-11-23)
Lymphangiomas of the tongue are rare, and their treatment is problematic. A 10 year-old patient with tongue lymphangioma who was previously treated with surgery and propranolol with no response was treated with sirolimus in our department. We used sirolimus with
Alvaro Ábarzúa-Araya et al.
Journal of the American Academy of Dermatology, 70(6), 1045-1049 (2014-03-25)
Infantile hemangiomas have a dramatic response to propranolol, a nonselective beta-blocker. However, this treatment is not risk-free and many patients are excluded because of respiratory comorbidities. Atenolol is a cardioselective beta-blocker that may have fewer adverse events. We sought to
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