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S2VPT10RE

Millipore

Millipore® Steritop® Vacuum Bottle Top Filter

pore size 0.1 μm, polyethersulfone membrane, funnel capacity 1000 mL, pack of 12 ea

Synonym(s):

SCVPT10RE, Steritop Quick Release-VP Sterile Vacuum Filtration System, bottle top sterile filter unit, bottle top vacuum filter, bottle top vacuum filtering unit

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About This Item

UNSPSC Code:
41104914
NACRES:
NB.24
Pricing and availability is not currently available.

material

polyethersulfone membrane
polystyrene bottle
polystyrene funnel(s)
polystyrene housing

Quality Level

400

sterility

sterile; irradiated

product line

Steritop®

feature

hydrophilic

packaging

pack of 12 ea

parameter

max. temp. at 45 °C

description

2.4 mL (hold-up volume)

technique(s)

sterile filtration: suitable

H

169 mm

capacity

1000 mL

diam.

13.5 cm

filter diam.

73 mm

filtration area

40 cm2

funnel capacity

1000 mL

matrix

Express PLUS™

pore size

0.1 μm pore size

fitting

inlet funnel
45 mm outlet thread(s)

shipped in

ambient

Related Categories

General description

This item is a direct replacement for SCVPT10RE
Work with ease and filter with confidence with Stericup® and Steritop® Filtration Systems. Stericup® and Steritop® vacuum sterile filtration devices use reliable, high-performance membranes for optimum sterile filtration of laboratory reagents, buffers, and media. These devices combine superior flow rates and throughput with low non-specific binding and a stable, no-tip design.

This Steritop ® 1000 mL bottle-top with 0.1 μm pore size polyethersulfone (PES) membrane filter unit can be used on bottles with 45 mm openings, designed for vacuum applications.

Application

For Research Use Only
Stericup® and Steritop® systems are designed to reduce foaming and protein denaturation while maximizing flow and can be used for sterile vacuum filtration of aqueous solutions such as tissue culture media and biological fluids.

  • Tissue culture media +/- additives
  • Buffers
  • Biological solutions

Features and Benefits

Bold product identification on the Steritop® filter funnel plainly displays membrane characteristics, including composition and pore size, for rapid, application-appropriate product selection.

Legal Information

EXPRESS PLUS is a trademark of Merck KGaA, Darmstadt, Germany
Millipore is a registered trademark of Merck KGaA, Darmstadt, Germany
STERITOP is a registered trademark of Merck KGaA, Darmstadt, Germany

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Articles

Mycoplasma Clearance Performance of Stericup® and Steritop® Filters

Evaluation of mycoplasma removal by sterilizing filtration using 0.1 µm PES and PVDF filters for cell culture media and buffer preparation.

Mycoplasma Clearance Performance of Stericup® and Steritop® Filters

Evaluation of mycoplasma removal by sterilizing filtration using 0.1 µm PES and PVDF filters for cell culture media and buffer preparation.

Mycoplasma Clearance Performance of Stericup® and Steritop® Filters

Evaluation of mycoplasma removal by sterilizing filtration using 0.1 µm PES and PVDF filters for cell culture media and buffer preparation.

Mycoplasma Clearance Performance of Stericup® and Steritop® Filters

Evaluation of mycoplasma removal by sterilizing filtration using 0.1 µm PES and PVDF filters for cell culture media and buffer preparation.

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Questions

1–10 of 15 Questions  

  1. What Bacterial Endotoxins Test is used?

    1 answer

    1. The test method used complies with USP 85 and EP 2.6.14 to ensure the absence of endotoxin in our products.

      Helpful?

  2. What is the chemical compatibility of the various Stericup® and Steritop® filters?

    What is the chemical compatibility of the various Stericup® and Steritop® filters?

    1 answer

    1. Please refer to our guide, "Chemical compatibility of filter components": https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/302/855/membrane-chemical-compatibility-ds2532en-ms.pdf

      Helpful?

  3. What is the expiration date of Stericup® and Steritop® filters?

    1 answer

    1. Typically 3 years from sterilization.

      Helpful?

  4. Which type of pump should be used with Stericup® and Steritop® vacuum filters?

    Which type of pump should be used with Stericup® and Steritop® vacuum filters?

    1 answer

    1. We recommend our Chemical Duty Pump: https://www.sigmaaldrich.com/product/mm/wp6111560

      Helpful?

  5. What is the maximum processing volume for Stericup® and Steritop® filters? Can I add more volume after initial filtration?

    1 answer

    1. All Stericup® and Steritop® filters were developed for single-use application. The maximum volume is dependent on the receiver bottle capacity. Stericup® filters come with a receiver bottle with a specified maximum volume. For Steritop® filters, the maximum recommended volume is 2 L with an appropriate-sized receiver bottle. Larger processing volumes can result in membrane fouling, increase chance of spillage and contamination, and lead to possible airlock*.
      *Note that devices with PES membranes can airlock if filtered to dryness. Some liquid must be left on top of the filter, then the system stopped, receiver changed or emptied, and more sample volume added before restart. This increases the chance of spillage.

      Helpful?

  6. The User Guide says “Use only glass or plastic bottles designed for vacuum applications”. Can you specify which bottles are compatible?

    1 answer

    1. Steritop® Quick Release bottle top units require a vacuum-rated receiver bottle with either a GL33 or GL45 mm closure thread as specified. Steritop® E bottle top units require a vacuum-rated receiver bottle with a GL45 mm closure thread. Bottles no larger than 2 L should be used.
      Glass bottles, GL33:
      • Wheaton media bottles (glass), 500 mL (Product Z364886)
      • Wheaton media bottles (glass), 1 L (Product Z364894)
      Glass bottles, GL45
      • Corning® glass media storage bottle, 125 mL (Product CLS1399125)
      • Corning® glass media storage bottle, 250 mL (Product CLS1399250)
      • Corning® glass media storage bottle, 500 mL (Product CLS1399500)
      • Corning® glass media storage bottle, 1 L (Product CLS13991L)
      • Pyrex® round media storage bottle, 500 mL (Product CLS1395500)
      • Pyrex® round media storage bottle, 1 L (Product CLS13951L)
      • KIMBLE® KIMAX® Media bottle, 250 mL (Product DWK14395250)
      • KIMBLE® KIMAX® Media bottle, 500 mL (Product DWK14395500)
      • KIMBLE® KIMAX® Media bottle, 1 L (Product DWK143951000)
      Plastic (pre-sterile) bottles, GL45:
      • Stericup® Quick Release Receiver flask, 250 mL (Product S200B02RE)
      • Stericup® Quick Release Receiver flask, 500 mL (Product S200B05RE)
      • Stericup® Quick Release Receiver flask, 1000 mL (Product S200B10RE)

      Helpful?

  7. What is the maximum vacuum pressure for filtration?

    1 answer

    1. 700 mm Hg (27.5” Hg, 0.9 bar) differential vacuum at 25 °C (77 °F)

      Helpful?

  8. What leachables are detected during filtration processes using Stericup® filters?

    1 answer

    1. We have not performed extractables/leachables studies for our Stericup® filters.

      Helpful?

  9. What is the difference between classic Stericup® filters and Stericup® “Quick Release” filters?

    1 answer

    1. Stericup® Quick Release, or “QR”, filters feature a connection between funnel filter and receiver bottle that requires only a quarter-turn release to facilitate funnel removal. These filters come fully engaged – there is no need to tighten before use. The receiver bottle cap has flanges on the top surface to improve grip, as well as a positive lock stop to ensure a leak-proof seal with the receiver bottle. Other improvements include a large, frosted writing surface on the receiver bottle and a lighter cap color to facilitate labelling, more prominent volume markings on the filtration funnel and receiver bottle, and a product label with a peel-off lot record strip on the bag for easy viewing in storage.

      Helpful?

  10. Are Stericup® and Steritop® filters GMP-certified?

    1 answer

    1. No, Stericup® and Steritop® devices are not GMP-approved.

      Helpful?

1–10 of 15 Questions  

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