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P35200

Sigma-Aldrich

Phenylsuccinic acid

98%

Synonym(s):

(±)-Phenylsuccinic acid

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About This Item

Linear Formula:
HO2CCH2CH(C6H5)CO2H
CAS Number:
635-51-8
Molecular Weight:
194.18
Beilstein:
1875051
EC Number:
211-238-1
MDL number:
MFCD00004256
UNSPSC Code:
12352100
PubChem Substance ID:
24898421
NACRES:
NA.22

Quality Level

200

Assay

98%

form

powder

mp

166-168 °C (lit.)

SMILES string

OC(=O)CC(C(O)=O)c1ccccc1

InChI

1S/C10H10O4/c11-9(12)6-8(10(13)14)7-4-2-1-3-5-7/h1-5,8H,6H2,(H,11,12)(H,13,14)

InChI key

LVFFZQQWIZURIO-UHFFFAOYSA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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T Bruhn et al.
Journal of neuroscience research, 46(2), 198-203 (1996-10-15)
Swelling-induced release of taurine was investigated in vivo in hippocampus by microdialysis or in vitro in cultured neocortical neurons or astrocytes. Swelling was induced either by increasing the extracellular K+ concentration or by exposing the cells to hyposmotic conditions. It
R Huang et al.
Neuroscience letters, 183(1-2), 22-26 (1995-01-02)
Phenylsuccinate is an inhibitor of cytosolic glutamate formation from extracellular glutamine in cultured cerebellar granule cell neurons, a glutamatergic preparation. It prevents anoxic cell death in these cells as indicated by decreased lactate dehydrogenase (LDH) release and by the morphological
Qing-Song Ye et al.
Archiv der Pharmazie, 340(11), 599-602 (2007-10-10)
Four diam(m)ineplatinum(II) complexes containing beta-phenylisosuccinate as the leaving groups were prepared, characterized, and evaluated for their cytotoxicity against A549/ATCC human lung cancer cell line and SGC-7901 human gastric cancer cell line. One of the complexes, (trans-1R,2R-diaminocyclohexane)-beta-phenylisosuccinatoplatinum(II) 4, was much more
R Svarna et al.
Neurochemical research, 21(5), 603-608 (1996-05-01)
The effect of aminooxyacetic acid (AOAA), NH4+, phenylsuccinate (Phs), ketone bodies (KB) and glutamine (Gln), that might interfere with the biosynthesis of neurotransmitter glutamate on the K(+)-evoked Ca(2+)-dependent release of D-[3H]aspartate from rat cerebellar slices was studied. Therefore slices were
A Atlante et al.
FEBS letters, 396(2-3), 279-284 (1996-11-04)
In this study we have investigated hydroxyproline transport in rat heart mitochondria and, in particular, in heart left ventricle mitochondria isolated from both spontaneously hypertensive and Wistar-Kyoto rats. Hydroxyproline uptake by mitochondria, where its catabolism takes place, occurs via a
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