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900743

Sigma-Aldrich

Branched PEI-g-PEG

PEG Mn 5,000

Synonym(s):

Branched polyethylenimine-graft-poly(ethylene glycol), PEI-g-PEG, PEI-PEG

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About This Item

Linear Formula:
H3CO(CH2CH2O)nC10H18N2O3(NHCH2CH2)mNH2
UNSPSC Code:
12162002
NACRES:
NA.23

form

liquid

Quality Level

100

mol wt

PEG Mn 5,000

storage temp.

2-8°C

Application

Branched PEI-g-PEG, PEG Mn 5000 was derived from Sigma-Aldrich Product 408727. Based upon an approximate Mw of 25,000 for the branched PEI, Product 900926 contains approximately 15 grafted PEG chains per PEI unit (by NMR).

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Katharina Ladewig et al.
Journal of biomedical materials research. Part A, 102(7), 2137-2146 (2013-07-31)
High molecular weight (MW) polyethyleneimine (PEI) has been successfully used for the transfection of a broad variety of cell lines. In contrast to low MW PEI, which exhibits low transfection efficiencies but also low cytotoxicity, high MW PEI-mediated transfection achieves
Chunxi Liu et al.
Biomaterials, 34(10), 2547-2564 (2013-01-22)
Co-delivery of nucleic acids and chemotherapeutics has a potential to efficaciously treat human diseases via their synergetic effects. Activable therapeutic tools at the nanoscale are suitable platforms for combination therapy. In this study, we have developed a multifunctional nanoscaled delivery
Jing Wang et al.
Biomaterials science, 4(9), 1351-1360 (2016-07-19)
Zwitterionic poly(carboxybetaine) (PCB), poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC) and non-ionic poly(ethylene glycol) (PEG), which have similar degrees of polymerization, were grafted to branched polyethyleneimine (PEI) to generate PCB-grafted PEI (PEI-PCB), PMPC-grafted PEI (PEI-PMPC) and PEG-grafted PEI (PEI-PEG) copolymers, respectively. These grafted PEI

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