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559091

Sigma-Aldrich

Ethyl (2-chlorobenzoyl)acetate

≥95%

Synonym(s):

Ethyl (o-chlorobenzoyl)acetate, Ethyl 3-(2-chlorophenyl)-3-oxopropanoate, NSC 158136

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About This Item

Linear Formula:
ClC6H4COCH2CO2C2H5
CAS Number:
Molecular Weight:
226.66
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Pricing and availability is not currently available.

Quality Level

Assay

≥95%

refractive index

n20/D 1.540 (lit.)

bp

221-222 °C (lit.)

density

1.206 g/mL at 25 °C (lit.)

functional group

chloro
ester
ketone

SMILES string

CCOC(=O)CC(=O)c1ccccc1Cl

InChI

1S/C11H11ClO3/c1-2-15-11(14)7-10(13)8-5-3-4-6-9(8)12/h3-6H,2,7H2,1H3

InChI key

DLFBNTUSDQSFOF-UHFFFAOYSA-N

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GF41894062GF60008486GF00134288
assay

100%

assay

100%

assay

100%

assay

100%

manufacturer/tradename

Goodfellow 190-749-33

manufacturer/tradename

Goodfellow 418-940-62

manufacturer/tradename

Goodfellow 600-084-86

manufacturer/tradename

Goodfellow 001-342-88

resistivity

8.37 μΩ-cm

resistivity

8.37 μΩ-cm

resistivity

8.37 μΩ-cm

resistivity

8.37 μΩ-cm

mp

156.6 °C (lit.)

mp

156.6 °C (lit.)

mp

156.6 °C (lit.)

mp

156.6 °C (lit.)

density

7.3 g/mL at 25 °C (lit.)

density

7.3 g/mL at 25 °C (lit.)

density

7.3 g/mL at 25 °C (lit.)

density

7.3 g/mL at 25 °C (lit.)

Application

Ethyl (2-chlorobenzoyl)acetate may be used to synthesize ketosplitomicin derivative[1] and ethyl 6-(2-chlorophenyl)-2,2-dimethyl-4-oxo-2,3-dihydro-4Hpyran-5-carboxylate.[2]
Reactant for:
  • Cerium ammonium nitrate-mediated oxidative coupling
  • Hydrosilylation reactions
  • Preparation of diaryl-substituted pyrazoles as potent CCR2 receptor antagonists
  • Preparation of potential herbicidal agents
  • Ruthenium-catalyzed asymmetric hydrogenation

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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