Peptide sequence around phosphorylation site of threonine 508 (R-Y-T(p)-V-V), according to the protein LIMK1.
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Target description
Protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. Isoform 3 has a dominant negative effect on actin cytoskeletal changes. May be involved in brain development.
Physical form
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
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