Skip to Content
Merck
All Photos(2)

Key Documents

View All Documentation

R0500

Sigma-Aldrich

Reichstein′s substance S

≥98% purity, powder

Synonym(s):

11-Deoxy-17-hydroxycorticosterone, 11-Deoxycortisol, 17α,21-Dihydroxy-4-pregnene-3,20-dione, 17α-Hydroxycortexone, 17,21-Dihydroxy-4-pregnene-3,20-dione, 17,21-Dihydroxyprogesterone, 4-Pregnene-17α,21-diol-3,20-dione, Cortexolone, Reichstein’s Compound S

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Empirical Formula (Hill Notation):
C21H30O4
CAS Number:
152-58-9
Molecular Weight:
346.46
EC Number:
205-805-2
MDL number:
MFCD00003662
UNSPSC Code:
12171500
PubChem Substance ID:
24278671
NACRES:
NA.47
Pricing and availability is not currently available.

Product Name

Reichstein′s substance S, ≥98%

Quality Level

200

Assay

(Infrared Spectrum: Conforms to Structure)
≥98%

form

powder

technique(s)

titration: suitable

mp

208 °C (dec.) (lit.)

solubility

ethanol: 50 mg/mL, clear, colorless to faint yellow or tan

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2CC[C@@]4(C)[C@H]3CC[C@]4(O)C(=O)CO

InChI

1S/C21H30O4/c1-19-8-5-14(23)11-13(19)3-4-15-16(19)6-9-20(2)17(15)7-10-21(20,25)18(24)12-22/h11,15-17,22,25H,3-10,12H2,1-2H3/t15-,16+,17+,19+,20+,21+/m1/s1

InChI key

WHBHBVVOGNECLV-OBQKJFGGSA-N

Looking for similar products? Visit Product Comparison Guide

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCW9239
MKCV5201
MKCV2807
MKCS5779
MKCQ5343

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

In vitro effects of different steroid hormones on superoxide anion production of human neutrophil granulocytes
Gabor Bekesi
Steroids (2000)
E O Yablokov et al.
The Journal of steroid biochemistry and molecular biology, 208, 105793-105793 (2020-12-04)
Steroidogenesis is strictly regulated at multiple levels, as produced steroid hormones are crucial to maintain physiological functions. Cytochrome P450 enzymes are key players in adrenal steroid hormone biosynthesis and function within short redox-chains in mitochondria and endoplasmic reticulum. However, mechanisms
Seiichi Sakamoto et al.
Journal of natural medicines, 72(1), 32-42 (2017-11-23)
Immunoassays are antibody-based analytical methods for quantitative/qualitative analysis. Since the principle of immunoassays is based on specific antigen-antibody reaction, the assays have been utilized worldwide for diagnosis, pharmacokinetic studies by drug monitoring, and the quality control of commercially available products.
Roux?s Arch. Dev. Biol. (2000)
Steven M Weldon et al.
The Journal of pharmacology and experimental therapeutics, 359(1), 142-150 (2016-08-03)
The mineralocorticoid aldosterone is an important regulator of blood pressure, volume, and electrolyte balance. However, excess aldosterone can be deleterious as a driver of vascular remodeling and tissue fibrosis associated with cardiometabolic diseases. Aldosterone synthase (AS) inhibitors (ASI) attenuate the
View All Related Papers

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service