L3265

Lipoteichoic acid from Bacillus subtilis

• CAS Number: 56411-57-5
• MDL number: MFCD00131526
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• biological source: Bacillus subtilis
• Quality Level: 200
• form: lyophilized powder
• lipid type: polymerizable lipids
• shipped in: ambient
• storage temp.: 2-8°C

Description

Biochem/physiol Actions

Lipoteichoic acid (LTA) is a complex component of cell walls of Gram-positive bacteria that are involved in a wide range of cell processes such as the stimulation of immune responses and cell signaling pathways. LTA differs between species of gram-positive bacteria. Lipoteichoic acid from Bacillus subtilis may be used to compare its structure, immunogenicity and functions versus other bacterial LTAs.

Lipoteichoic acid (LTA) is a teichoic acid attached to a lipid abundant on Gram-positive bacteria cell wall. LTA is a pathogen-associated molecular-patterns (PAMP) recognized by Toll-like receptor 2 (TLR2), This recognition leads to the activation of NF-kB.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves