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A7165

Sigma-Aldrich

1,5-Anhydro-D-sorbitol

crystalline, ≥98.0% (TLC)

Synonym(s):

1,5-Anhydro-D-glucitol

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About This Item

Empirical Formula (Hill Notation):
C6H12O5
CAS Number:
154-58-5
Molecular Weight:
164.16
EC Number:
205-829-3
MDL number:
MFCD00067386
UNSPSC Code:
12352201
PubChem Substance ID:
24891181
NACRES:
NA.25

Quality Level

200

Assay

≥98.0% (TLC)

form

crystalline

color

white

solubility

water: 49.00-51.00 mg/mL, clear, colorless

SMILES string

OCC1OCC(O)C(O)C1O

InChI

1S/C6H12O5/c7-1-4-6(10)5(9)3(8)2-11-4/h3-10H,1-2H2

InChI key

MPCAJMNYNOGXPB-UHFFFAOYSA-N

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Application

1,5-Anhydro-D-sorbitol, a cyclic polyol, is a metabolic product of 1,5 anhydro-D-fructose. 1,5-Anhydro-D-sorbitol is used as a reference in analytical procedures that assess the metabolism of 1,5 anhydro-D-fructose, a food supplement with potential benefits as an antioxidant, antimicrobial, and antidiabetic agent.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000243742
0000243742
0000208320
0000205619
0000160872

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Masaya Sakamoto et al.
Cardiovascular diabetology, 11, 92-92 (2012-08-08)
No previous studies have compared the DPP-4 inhibitors vildagliptin and sitagliptin in terms of blood glucose levels using continuous glucose monitoring (CGM) and cardiovascular parameters. Twenty patients with type 2 diabetes mellitus were randomly allocated to groups who received vildagliptin
Lingzi Li et al.
Diabetes, 68(12), 2272-2286 (2019-09-21)
Identification of individuals with decreased functional β-cell mass is essential for the prevention of diabetes. However, in vivo detection of early asymptomatic β-cell defect remains unsuccessful. Metabolomics has emerged as a powerful tool in providing readouts of early disease states
Roy Beck et al.
Pediatric diabetes, 12(8), 690-695 (2011-04-19)
To describe the interrelationships of glycemic control measures: hemoglobin A1c (HbA1c), glycated albumin, fructosamine, 1,5-anhydroglucitrol (1,5-AG), and continuous glucose monitoring (CGM) in children and adolescents with type 1 diabetes. In total, 26 subjects of age 4-17 had HbA1c measurement followed
Stephen P Juraschek et al.
Clinical chemistry, 58(12), 1648-1655 (2012-09-29)
1,5-Anhydroglucitol (1,5-AG), fructosamine, and glycated albumin are of increasing interest as alternative measures of hyperglycemia. We characterize the associations of these nontraditional glycemic markers with hemoglobin A(1c) (Hb A(1c)) and fasting glucose and assess their ability to identify people with
Nobuya Inagaki et al.
The lancet. Diabetes & endocrinology, 3(3), 191-197 (2015-01-23)
Trelagliptin is a novel once-weekly oral DPP-4 inhibitor. We assessed the efficacy and safety of trelagliptin versus the daily oral DPP-4 inhibitor alogliptin in Japanese patients with type 2 diabetes. We did a randomised, double-blind, active-controlled, parallel-group, phase 3, non-inferiority
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