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PHR1274

Supelco

Melamine

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

2,4,6-Triamino-1,3,5-triazine, sym-Triaminotriazine

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About This Item

Empirical Formula (Hill Notation):
C3H6N6
CAS Number:
Molecular Weight:
126.12
Beilstein:
124341
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

Agency

traceable to USP 1379183

API family

melamine

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

>300 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

Nc1nc(N)nc(N)n1

InChI

1S/C3H6N6/c4-1-7-2(5)9-3(6)8-1/h(H6,4,5,6,7,8,9)

InChI key

JDSHMPZPIAZGSV-UHFFFAOYSA-N

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General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Melamine is a nitrogen-rich chemical employed in the production of plastics, resins, laminates, adhesives as well as flame retardants. It may also be utilized as a fertilizer. It is one of the metabolites of cyromazine, which is approved for use as an insecticide on a wide range of vegetable crops.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC3464 in the slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Pictograms

Health hazard

Signal Word

Warning

Hazard Statements

Hazard Classifications

Carc. 2 - Repr. 2 - STOT RE 2

Target Organs

Urinary tract

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

572.0 °F - closed cup

Flash Point(C)

300 °C - closed cup


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Method development and validation for melamine and its derivatives in rice concentrates by liquid chromatography. Application to animal feed samples
Mu?iz-Valencia R, et al.
Analytical and Bioanalytical Chemistry, 392(3), 523-531 (2008)
N Vasimalai et al.
Biosensors & bioelectronics, 42, 267-272 (2012-12-05)
We wish to report a simple and sensitive method to determine the melamine in milk and infant formulas using 3-amino-5-mercapto-1,2,4-triazole capped gold nanoparticles (AMTr-AuNPs) as fluorophore. The AMTr-AuNPs were synthesized by a wet chemical method and were characterized by high-resolution
Anthony Kai-ching Hau et al.
Journal of the American Society of Nephrology : JASN, 20(2), 245-250 (2009-02-06)
The toxicity of melamine caught the attention of physicians as a result of a recent spate of renal injury after exposure to melamine-tainted milk in China. Melamine is an organic nitrogenous compound used in the production of plastics, dyes, fertilizers
Simon A Haughey et al.
Food chemistry, 136(3-4), 1557-1561 (2012-12-01)
Soya bean products are used widely in the animal feed industry as a protein based feed ingredient and have been found to be adulterated with melamine. This was highlighted in the Chinese scandal of 2008. Dehulled soya (GM and non-GM)
Ana Paula Craig et al.
Annual review of food science and technology, 4, 369-380 (2013-01-10)
Surface-enhanced Raman spectroscopy (SERS) is an advanced Raman technique that enhances the vibrational spectrum of molecules adsorbed on or in the vicinity of metal particles and/or surfaces. Because of its readiness, sensitivity, and minimum sample preparation requirements, SERS is being

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